BACKGROUND Numerous studies have shown decreased perfusion in the prefrontal cortex following mild traumatic brain injury (mTBI). However, similar hypoperfusion can also be observed in depression. Given the high prevalence of depressive symptoms following mTBI, it is unclear to what extent depression influences hypoperfusion in TBI. METHODS Mild TBI patients without depressive symptoms (mTBI-...

myocardial perfusion spect imaging with tc99m-sestamibi is the most accurate non-invasive means of detecting coronary artery disease and assessing the severity of perfusion abnormalities in the patients with coronary stenosis. though simple and straight forward the results produced by the technique is very much affected by the details being used. one of the main problems with the test, which ha...

coronary heart disease (cad) is the leading cause of death specially among elderly. coronary angiography is the best diagnostic method in the patients, but is unfortunately an invasive procedure with its inherent risks. myocardial perfusion scan is a noninvasive and sensitive method for evaluation of cad and is suggested by many investigators in recent years. in this study, 64 patients who had ...

objective: the morphology of anterior cerebral artery (aca) in patients with hydrocephalus was analyzed (hcp), and its importance was discussed in maintaining cerebral perfusion. materials & methods: two groups were created for the study. group 1; patients with hydrocephalus and group 2; as control group without hcp. in both groups, the length of the a2 segment of aca was measured from its orig...

introduction: we aimed to assess whether the vasodilator effect of oral dipyridamole on the left ventricular systolic function in patients with suspected cad is different from that of intravenous (iv) dipyridamole using tc-99m mibi myocardial perfusion gated spect. methods: eighty-nine patients (17 m / 72 w; 61 ± 10 years) were enrolled in this study. the patients underwent a dipyridamole stres...

background: pre-clinical investigation of stem cells for repairing damaged myocardium predominantly used rodents, however large animals have cardiac circulation closely resembling the human heart. the aim of this study was to evaluate whether spect/ct myocardial perfusion imaging (mpi) could be used for assessing sheep myocardium following an acute myocardial infarction (mi) and response to int...

AIMS To determine in a multicentre, multivendor trial the diagnostic performance for perfusion-cardiac magnetic resonance (perfusion-CMR) in comparison with coronary X-ray angiography (CXA) and single-photon emission computed tomography (SPECT). METHODS AND RESULTS Of 241 eligible patients from 18 centres, 234 were randomly dosed with 0.01, 0.025, 0.05, 0.075, or 0.1 mmol/kg Gd-DTPA-BMA (Omni...

99mTC (single photon emission computed tomography) (HMPAO SPECT) was carried out during 16 frontal-lobe seizures in 15 patients. Focal changes in regional cerebral blood flow were seen during all seizures. In 9 of 16 seizures SPECT showed hyperperfusion localized to one frontal lobe. In 1 of 16 seizures ictal hypoperfusion was seen in one frontal lobe. In 2 of 16 seizures there was hyperperfusi...

We will discuss clinical and radiological findings of a woman who attempted suicide by hanging. We report a 19-year-old women attempted suicide by hanging herself. There was no known period of global brain ischemia. She had a score of 7 on the Glasgow coma scale. CT scan showed bitemporal hippocampal atrophy and SPECT showed non-activated area on right temporal and temporo-occipital regions. Th...

Quantitative evaluation of brain MRI/SPECT fusion methods for normal and in particular pathological datasets is difficult, due to the frequent lack of relevant ground truth. We propose a methodology to generate MRI and SPECT datasets dedicated to the evaluation of MRI/SPECT fusion methods and illustrate the method when dealing with ictal SPECT. The method consists in generating normal or pathol...