intraocular metastatic tumors have been increasingly reported in the recent past. unlike choroidal metastasis, metastasis to retina is very rare and so far has been reported in very few case reports only. case presentation : a 56 year-old male who presented with a history of adenocarcinoma of the cecum and underwent lap colectomy for the primary cecal tumor, received adjuvant chemotherapy for a...

ba c k g r o u nd: skin  metastases occur  in  1-5%  of  solid  tumors  and  are  rarely the presenting sign of internal malignancies. certain features in skin lesions raise suspicion of metastasis from solid tumors. c a s e presentation: in this article a 61-year-old woman is presented with erythematous skin nodules  in  upper  abdomen  and  chest. histopathological evaluation  of  lesions sug...

Context. Breast cancer (BC) in men is a rare condition, corresponding to 1% of all neoplasms in this gender. Some studies show that up to 93% of BC cases in men are advanced disease. If its occurrence constitutes an uncommon fact, the appearance of a metastasis to the central nervous system (CNS) is extremely rare. The objective of the present study is to present the case of a male patient, bea...

Brain metastasis in patients with cancer can be indicative of multisystem spread or lead to neurological demise if not locally controlled, and is associated with poor survival and high morbidity. Compared with metastasis to other areas of the body, brain metastasis possesses a unique biology that confers high resistance to systemic therapies. This phenomenon has been historically attributed to ...

BACKGROUND It is estimated that at least 200 000 cases of brain metastases occur each year in the US, which is 10 times the number of patients diagnosed with primary brain tumors. Brain metastasis is associated with poor prognosis, neurological deterioration, diminished quality of life, and extremely short survival. Favorable interactions between tumor cells and cerebral microvascular endotheli...

Biologic and therapeutic advances in melanoma brain metastasis are hampered by the paucity of reproducible and predictive animal models. In this work, we developed a robust model of brain metastasis that empowers quantitative tracking of cellular dissemination and tumor progression. Human melanoma cells labeled with superparamagnetic iron oxide nanoparticles (SPION) were injected into the left ...

a 49 year old woman diagnosed as a cervical cancer patient, after receiving appropriate treatment experienced metastasis in her abdominopelvic cavity. after aggressive management, she was well for a while. however, she developed to a poor condition consisting of urologic, gastroenterological, hematologic and neurologic problems just in a short time. in the course of hospital she presented one s...

A 61-year-old male was admitted to the hospital with tumors in the scalp (A), face (B), and neck (C) that had been present for four month with an acute decrease in visual acuity. These tumors have progressed to ulceration. Clinical examination observed although limited 3 lumps varying sizes from 1,5mm to 2 cm and ulcerated at the center. Dermoscopy was objective polymorphic vessels. The differe...

Biologic and therapeutic advances in melanoma brain metastasis are hampered by the paucity of reproducible and predictive animal models. In this work, we developed a robust model of brain metastasis that empowers quantitative tracking of cellular dissemination and tumor progression. Human melanoma cells labeled with superparamagnetic iron oxide nanoparticles (SPION) were injected into the left ...

The symptomatic choroidal metastasis is a rare manifestation of lung cancer. The aim of this study was to present a clinical case of choroidal metastasis associated with multiple intracerebral metastases from a papillary adenocarcinoma of the lung diagnosed simultaneously with its metastases. We present the case of a 40-year-old male patient, smoker, admitted to the Neurosurgery Clinic II, "Pro...