BACKGROUND We reviewed the literature on published cases of progressive facial hemiatrophy (Parry-Romberg syndrome) to identify possible pathophysiological mechanisms of the syndrome. OBJECTIVE To describe the somatosensory phenotype of a previously unreported patient with progressive facial hemiatrophy and facial pain. DESIGN Case report and 4-month follow-up period. SETTING University-b...

Parry-Romberg syndrome or progressive facial hemiatrophy (PFH) is a rare disease of unknown etiology characterized by atrophy of the skin and subcutaneous tissue on one side of the face. The authors present the case of a 32-year-old woman with PFH who had migraine and an intracranial aneurysm. The findings support the hypothesis that the disease could be related to a neural crest migration diso...

Parry Romberg syndrome (PRS), also referred to as progressive hemifacial atrophy, facial hemiatrophy, or idiopathic was first described by C and M Romberg.1 It manifests in the two decades morphologically normal-born individuals. commonly affects one more dermatomes trigeminal nerve territory. has an early onset of ophthalmic neurological involvement a variable maxillo-facial cardiac involvemen...

Hemiconvulsion-hemiplegia-epilepsy syndrome (HHE) is a rare outcome of prolonged hemiconvulsion that is followed by diffuse unilateral hemispheric edema, hemiplegia, and ultimately hemiatrophy of the affected hemisphere and epilepsy. Here, we describe the case of a 3-year-old male with a 1;3 translocation leading to a terminal 1q43q44 deletion and a terminal 3p26.1p26.3 duplication that develop...