BACKGROUND AND OBJECTIVE A three-dimensional scaffold may play an important role in periodontal tissue engineering. We prepared bio-safe collagen hydrogel, which exhibits properties similar to those of native extracellular matrix. The aim of this study was to examine the effect of implantation of collagen hydrogel/sponge scaffold on periodontal wound healing in class II furcation defects in dog...

OBJECTIVE This study was conducted to evaluate the microshear bond strength (μSBS) and ultramorphological characterization of glass ionomer (GI) cements; conventional GI cement (Fuji IX, CGI), resin modified GI (Fuji II LC, RMGI) and nano-ionomer (Ketac N100, NI) to enamel, dentin and cementum substrates. MATERIALS AND METHODS Forty-five lower molars were sectioned above the cemento-enamel ju...

Background: Intentional replantation of periodontally involved teeth has been reported to result in unfavorable healing like root resorption and ankylosis. However, many recent clinical reports using enamel matrix derivative (EMD) showed a good outcome based on clinical and radiographic examination. However, histological findings are lacking. The purpose of this study was to evaluate healing af...

OBJECTIVE The objective of this study was to investigate the cementum status in natural teeth opposing implant-supported bridgework. METHODS Maxillary premolars and molars opposing immediate-loading (IL) and delayed-loading (DL) mandibular implant-supported bridgework in 4 Macaca fascicularis were harvested after 3 months of functional loading. Another 2 monkeys without mandibular fixed prost...

The aim of this study was to evaluate the in vitro diffusion of synthetic salmon calcitonin (CT), used as an intracanal medication, to the external root surface, with or without the presence of intact root cementum. Fifty-four human central incisors were used in the experiment, and were divided into two groups of 21 (test groups) and two groups of 6 teeth (control groups). After root canal prep...

Regeneration of periodontal tissues requires an integrated approach to the restoration ligament, cementum, and alveolar bone surrounding teeth. Current strategies in endogenous regenerative dentistry widely use biomaterials, particular decellularized extracellular matrix (dECM), facilitate recruitment populations resident cells into damaged stimulate their proliferation differentiation. The pur...

The concentration of structural hydroxyl groups in the apatite mineral of enamel, dentin and cementum of healthy human teeth was estimated by reference to stoichiometric hydroxyapatite to be 73 +/- 3, 18 +/- 2 and 18 +/- 1%, respectively.

Background: Management of the necrotic immature permanent incisor has long been a difficult clinical problem. The Frank technique of multiple applications of calcium hydroxide, although often successful, required multiple appointments and could take years to complete. More recently, the single-appointment mineral trioxide aggregate (MTA) apical plug technique reduced the multiple appointments t...