Background: The aim was to evaluate the benefit of technical advances for treatment planning: introduction of a hydrogel spacer, VMAT (volumetric modulated arc therapy) and a single biological organ at risk objective for the rectum and bladder. Initial standard was a step-and-shoot IMRT (intensity modulated radiotherapy) without a spacer and conventional organ at risk objectives.  Material...

Kaplan, L; Shorez, JP; Baker, KC; DeLandsheer, T; Verner, J William Beaumont Hospitals, Royal Oak, MI Senior author: [email protected] Introduction Antibiotic-loaded polymethyl-methacrylate (PMMA) bone cement spacers are currently used to treat patients with an infected total joint arthroplasty. Mixing antibiotics into PMMA spacers offers distinct advantages over oral and/or intravenous administ...

A 76 year old female, with a background history of eczema and iatrogenic Cushing syndrome, received right total knee replacement for her osteoarthritis. In the early post-operative period, small amount discharge was noted from surgical wound. The wound swab culture yielded candida species. It regarded as contamination initially. Half later, she presented subcutaneous abscess around knee. Aspira...

Ferry T, et al. BMJ Case Rep 2017. doi:10.1136/bcr-2017-221743 Description A 54-year-old patient with haemophilia and hepatitis C virus infection experienced acute left prosthetic joint infection due to Klebsiella pneumoniae and Staphylococcus aureus following unipolar exchange in September 2015. As the outcome was not favourable with bloody discharge despite haemophilic factor substitution, a ...

Periprosthetic joint infection (PJI) is one of the most frequent reasons for painful shoulder arthroplasties and revision surgery of shoulder arthroplasties. Cutibacterium acnes (Propionibacterium acnes) is one of the microorganisms that most often causes the infection. However, this slow growing microorganism is difficult to detect. This paper presents an overview of different diagnostic test ...

BACKGROUND Periprosthetic infections remain a devastating problem in the field of joint arthroplasty. In the following study, the results of a two-stage treatment protocol for chronic periprosthetic infections using an intraoperatively molded cement prosthesis-like spacer (CPLS) are presented. METHODS Seventy-five patients with chronically infected knee prosthesis received a two-stage revisio...

AIM The present study was to evaluate the space provided for the temporary luting cement, after the application of various coats of die spacers, during the fabrication of provisional crowns and bridges. MATERIALS AND METHODS A total of 50 specimens of dental stone with provisional crowns on all these samples were prepared and were divided into five groups based on the application of various c...

Introduction. Periprosthetic joint infections (PJIs) are the primary cause of early failure of the total knee arthroplasty (TKA). Polymicrobial TKA infections are often associated with a higher risk of treatment failure. The aim of the study was to assess the efficacy of ertapenem loaded spacers in the treatment of polymicrobial PJI. Methods. There were 18 patients enrolled; nine patients with ...