OBJECTIVE To determine the incidence of clinically relevant potential drug-drug interactions (DDIs) in a large population of ambulatory patients utilizing a computerized, retrospective drug utilization review (DUR) program followed by clinical pharmacist audit. METHODS The drug claims database included approximately 2.9 million patients with more than 30 million prescriptions dispensed in the...

BACKGROUND & OBJECTIVES Information available on drug consumption is inadequate in most low and middle income countries. This systematic review was conducted to analyse published work on drug utilization research/studies (DUR) in the SEARO region of WHO for study objectives, methodology, results and recommendations and to identify the need for improving DUR and the use of the ATC/DDD system. ...

BACKGROUND Canadians receive over 422 million prescriptions and spend over $26 billion annually on drugs. Yet, we do not systematically capture information on whether the right drugs reach the right people with the intended benefits, while avoiding unintended harm. It is important to identify and understand the effectiveness of approaches used to improve prescribing and medication use. OBJECT...

The kinetics of acetate utilization were examined for washed concentrated cell suspensions of two thermophilic acetotrophic methanogens isolated from a 58 degrees C anaerobic digestor. Progress curves for acetate utilization by cells of Methanosarcina sp. strain CALS-1 showed that the utilization rate was concentration independent (zero order) above concentrations near 3 mM and that acetate uti...

BACKGROUND Despite numerous reports of state Medicaid drug utilization review (DUR) programs, little data are available about the prevalence of drugrelated problems (DRPs) in Medicaid patients. A university-based, pharmacist-run DUR program for high utilizers was created as an alternative to imposition of a statutory limit of 7 medications per month in the Utah Medicaid program in 2002. The DUR...