cd19 is expressed on b- lineage cells and follicular dendritic cells and plays a key role in b cell malignancies and autoimmune diseases. thus, it has been considered as potential target for several monoclonal antibodies (mabs). for decades, chemotherapy has been known as one of the major antitumor therapies eradicating high proliferative tumor cells. but, anti- cd19 mabs developed for treating...

conclusions to our knowledge, this is the first chronic case confirmed by the prolonged presence of hev rna in china. it is also the first reported persistent hepatitis e infection caused by hev genotype 4. case presentation here we report a chinese boy with acute lymphoblastic leukemia, who developed hepatitis e during a period of intensive chemotherapy. twenty months after the initial infecti...

we report a case of membranoproliferative glomerulonephritis (mpgn) with igmκ light chain deposits in a patient with chronic hepatitis c infection and simultaneous onset of monoclonal igmκ gammopathy with concurrent small b-cell lymphoproliferative disease. the patient presented with hepatosplenomegaly and a uremic state that necessitated dialysis without any clinical signs of systemic disease ...

Diffuse large B-cell lymphoma can selectively and predominantly infiltrate lymph node sinuses this pattern has been recognized as an unusual morphologic variant of entity. Sinusoidal lymphomas with CD30 expression are even more rare.We present a 63-year-old female, who came in chief complaint mass the axillar region for 2 months. The lymphnode ultrasound revealed multiple suspicious lymphadenop...

Lymphomas are solid malignant tumors having a wide spectrum of clinical and pathological features. Non-Hodgkin’s lymphoma (NHL) is a subtype of lymphoma with two-thirds of the cases presenting as lymph node enlargement. The remaining one third of NHL cases has been reported in the extranodal sites, including the gastro intestinal tract, Waldeyer’s ring, bone, skin, and brain. Intraoral non-Hodg...

Background: The clinical presentation of non-Hodgkin lymphoma (NHL) varies tremendously depending upon the type of lymphoma and the areas of involvement. NHL can rarely present as an abdominal mass compressing the inferior vena cava. The clinical presentation due to obstruction of inferior vena cava has often been called the inferior vena cava syndrome (IVCS). It can present acutely or chronica...

Introduction: Central mucoepidermoid carcinoma (CMEC) is a rare primary intraosseous bony lesion. The mandible is more commonly affected than the maxilla. CMEC is frequently misdiagnosed radiographically and clinically as a benign odontogenic tumor or cyst. Case Presentation: We present a rare case with a secondary malignant neoplasm. A male patient was initially diagnosed with B-cell non-Hodg...

abstract background involvement of lacrimal apparatus by non hodgkin lymphoma as a first manifestation is extremely rare and only three cases have been reported in children. the purpose of this report is to determine the clinical characteristic of patient with primary involvement of lacrimal apparatus with lymphoma. case presentation a 7-year-old girl with history of tearing, gradually progress...