Background: The water-soluble extract of Ganoderma lucidum (Reishi) has been used as an immunomodulator to stimulate spleen cells proliferation and cytokine expression. Objective: To investigate the effect of Ganoderma lucidum (G. lucidum) on cytokine production by mice peritoneal macrophages. Methods: Mice peritoneal macrophages were prepared by intra-peritoneal injection of 5 ml cold PBS. Per...

A fuzzy goal programming-based approach is used to solve a proposed multi-objective linear programming model and simultaneously handle two important problems in cellular manufacturing systems, viz. cell formation and layout design. Considerations of intra-cell layout, the intra-cell material handling can be calculated exactly. The advantages of the proposed model are considering machining cost,...

Objective: To determine the association between inflammatory mast cells and various diseases of salivary glands.
 Material Methods: An experimental lab based descriptive study was done at institute pathology diagnostic medicine, Khyber medical university, Peshawar. Non probability, convenient sampling comprising n=71was tissue biopsies gland were collected from April, 2022 to Sept. 2022. G...

BACKGROUND The desmoplastic small round cell tumour is a rare and aggressive intra-abdominal neoplasia, with only 200 cases reported, and a higher incidence in men and predilection for the second decade of life. Histologically characterized by the presence of small nests of undifferentiated tumour cells, wrapped in fibrous desmoplastic stroma. CLINICAL CASE A 24 year old male started with abd...

introduction: hunger and reduction in regular energy intake can lead to a number of problems based on their intensity. for instance, low energy level can cause blood cell production to decline or it may pose a higher risk of anemia. it can also weaken the immune system and platelet aggregation or negatively affect clot formation. this study aimed to have a closer look at fasting and regular phy...

there is a new technique to measure total body water named bio-electrical impedance analysis (bia), used in healthy subjects and patients. bia determines the total body water (tbw), fat-free mass (ffm), body cell mass (bcm), extra cellular water (ecw), and intra cellular water (icw) in subjects without significant fluid and electrolyte imbalance. there are several methods such as segmental bia,...

Dendritic cells (DCs) are essential in T cell-mediated destruction of insulin-producing beta cells in the islets of Langerhans in type 1 diabetes. In this study, we investigated T cell induction of intra-islet DC maturation during the progression of the disease in both autoimmune-prone NOD and resistant C57BL/6 mice. We demonstrated steady-state capture and retention of unprocessed beta cell-de...