We compared the activities of telithromycin, erythromycin, azithromycin, josamycin, penicillin G, amoxicillin, cefpodoxime, and ceftriaxone against invasive and noninvasive non-penicillin-susceptible Streptococcus pneumoniae isolates recovered from children. Of the 186 isolates tested, 89% were positive for erm(B) by PCR. Telithromycin had the lowest MICs, with MICs at which 90% of the isolates...

Ro 41-3399 is a novel orally active ester of Ro 40-6890, an aminothiazolyl cephalosporin with potent in vitro activities against commonly encountered aerobic gram-positive bacteria (streptococci and methicillin-susceptible staphylococci) and gram-negative bacteria (members of the family Enterobacteriaceae, haemophili, meningococci, and gonococci). In terms of the MICs determined by the methods ...

Methicillin Resistant Staphylococcus aureus (MRSA) has been recently growing problem in small animal clinical practice due to increasing resistance to multiple number of antimicrobials. Present study reports about the antimicrobial susceptibility pattern of MRSA isolated from the dogs with recurrent pyoderma. Based on the cultural and biochemical studies 12 isolates were identified as Staphyloc...

Seven hundred twenty-three isolates of Moraxella catarrhalis obtained from outpatients with a variety of infections in 30 medical centers in the United States between 1 November 1994 and 30 April 1995 were characterized in a central laboratory. The overall rate of beta-lactamase production was 95.3%. When the National Committee for Clinical Laboratory Standards MIC interpretive breakpoints for ...

S-1090 is a new synthetic, nonesterified, oral cephalosporin with a broad spectrum of antibacterial activity. The activities of S-1090 against the causative organisms in the fields of obstetrics and gynecology are superior to those of the currently prescribed oral cephems, cefdinir, cefpodoxime, and cefaclor. The in vivo efficacy of S-1090 was evaluated using uterine endometritis of model rats....

Sir, Cat-scratch disease (CSD) is a benign, usually self-limited infection, characterized by a primary papulopustular skin lesion at the site of the scratch and is usually accompanied by an enlarged, localized lymph node. Traditionally, the clinical diagnosis of CSD was made when three of the following four criteria were met: (i) cat contact con¢rmed by the presence of cat scratch or primary sk...