نتایج جستجو برای: cecal ligation and puncture

تعداد نتایج: 16833185  

Journal: :Intensive care research 2022

Abstract Background Sepsis is the leading cause of death in hospitalized patients intensive care unit (ICU). Although substantial progress has been made studies on treatment sepsis, mortality rate remains extremely high. We have previously reported that electroacupuncture (EA) induced tolerance against but underlying mechanism unclear. Methods C57BL/6 mice were pretreated with EA before sepsis ...

A. Dadkhah, F. Fatemi, M.R. Zolfaghari, Sh. Ghanooni,

Background: Mentha piperita L. essential oils have different antibacterial activity. In the present study, we investigated the effect of &gamma–irradiation on the antibacterial activities of Mentha piperita L. essential oils in vitro and in vivo systems. Materials and Methods: The aerial parts of peppermint were irradiated in a cobalt60 source with 0, 10 and 25 kGy absorbed doses. Then, t...

Background: Sepsis or infection is the second leading cause of death in people who are intensive care units. Due to the side effects of NSAIDs drugs, the use of medicinal plants with anti-inflammatory such as Rosa (R.) damascene Mill. for treating and reducing the symptoms of the inflammation has been suggested. Objective: The current study aimed to evaluate the anti-inflammatory and antioxodan...

Journal: :Intensive Care Medicine Experimental 2021

Abstract Background To describe the effect of mechanical ventilation on diaphragm mitochondrial oxygen consumption, ATP production, reactive species (ROS) generation, and cytochrome c oxidase activity content, their relationship to strength in an experimental model sepsis. Methods A cecal ligation puncture (CLP) protocol was performed 12 rats while controls underwent sham operation. Half each g...

2013
Waka Takahashi Eizo Watanabe Lisa Fujimura Haruko Watanabe-Takano Hiroyuki Yoshidome Paul E Swanson Takeshi Tokuhisa Shigeto Oda Masahiko Hatano

INTRODUCTION It is not well understood whether the process of autophagy is accelerated or blocked in sepsis, and whether it is beneficial or harmful to the immune defense mechanism over a time course during sepsis. Our aim was to determine both the kinetics and the role of autophagy in sepsis. METHODS We examined autophagosome and autolysosome formation in a cecal ligation and puncture (CLP) ...

Journal: :Aging 2021

Septic shock is one of the most significant health concerns across world, involving hypo-perfusion and defects in tissue energy. The current study investigates role NLR family CARD domain containing protein 4 (NLRC4) septic shock-induced inflammatory reactions, lung injuries, dendritic cell (DC) apoptosis. mice models were established by modified cecal ligation puncture injected with retroviral...

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