Prikry asked if it is relatively consistent with the usual axioms of ZFC that every nontrivial ccc forcing adds either a Cohen or a random real. Both Cohen and random reals have the property that they neither contain nor are disjoint from an infinite set of integers in the ground model, i.e. they are splitting reals. In this note I show that that it is relatively consistent with ZFC that every ...

The efficiency and robustness of reliability methods are two important factors in the first-order reliability method (FORM). The conjugate choice control (CCC) and directional chaos control method (DCC) are developed to improve the robustness and efficiency of the FORM formula using the stability transformation method. In this paper, the CCC and DCC methods are applied for the reliability analy...

The capacities of indole-3-acetic acid (IAA) and gibberellin A(3) (GA(3)) to counteract the inhibitory effects of (2-chloroethyl) trimethylammonium chloride (CCC), 2-isopropyl-4-dimethylamino-5-methylphenyl-1-piperidinecarboxylate methyl chloride (Amo-1618), and N,N-dimethylaminosuccinamic acid (B-995) on hypocotyl elongation in light-grown cucumber (Cucumis sativus L.) seedlings were investiga...

Yoichiro Ito introduced countercurrent chromatography (CCC) in 1966, reporting the separation of blood plasma cells with a sealed helical tube. Since then, CCC has been a fertile ground for instrumental and technical innovation. The key innovation of CCC was to use centrifugal forces to retain the stationary liquid phase in the column in such a way that it is able to interact dynamically with t...

Hepatitis B virus (HBV) covalently closed circular (CCC) DNA is the source of HBV transcripts and persistence in chronically infected patients. The novel aspect of this study was to determine the effect of RNA interference (RNAi) on HBV CCC DNA when administered prior to establishment of HBV replication or during chronic HBV infection. HBV replication was initiated in HepG2 cells by transductio...

BACKGROUND Collateral growth in patients with coronary artery disease (CAD) is highly heterogeneous. Although multiple factors are thought to play a role in collateral development, the contribution of genetic factors to coronary collateral circulation (CCC) is largely unknown. The goal of this study was to assess whether functional single nucleotide polymorphisms (SNPs) in genes involved in vas...

Clear cell adenocarcinoma (CCC) of the ovary accounts for 10% of epithelial ovarian cancer and is a distinct entity from other epithelial ovarian carcinomas. It arises from the endometriosis. CCC has specific biological and clinical behavior. Compared with other histological types, CCC shows a chemoresistant phenotype, which leads to poorer prognosis. Thus, development of new target-based thera...

PURPOSE To compare the anterior lens capsulotomy edge tear strength created by manual continuous curvilinear capsulorhexis (CCC), femtosecond laser capsulotomy (FSLC), and a new automated precision pulse capsulotomy (PPC) device. DESIGN A 3-arm study in paired human cadaver eyes. PARTICIPANTS A total of 44 eye specimens from 22 donors in the United States. METHODS Capsulotomy was performe...

BACKGROUND Compassion and collaborative practice are individually associated with high quality healthcare. When combined in a compassionate collaborative care (CCC) practice framework, they are reported to improve health, strengthen care provision, and control health costs. Little is known about how to integrate and measure CCC, yet it is fundamentally applied in palliative and end-of-life care...

Several clinical trials to establish standard treatment modality for ovarian cancers included a high abundance of patients with serous histologic tumors, which were quite sensitive to platinum-based chemotherapy. On the other hand, ovarian tumor with rare histologic subtypes such as clear cell or mucinous tumors have been recognized to show chemo-resistant phenotype, leading to poorer prognosis...