Gaucher disease is an inherited metabolic disorder caused by mutations in the lysosomal enzyme acid-beta-glucosidase (GlcCerase). We recently determined the x-ray structure of GlcCerase to 2.0 A resolution (Dvir, H., Harel, M., McCarthy, A. A., Toker, L., Silman, I., Futerman, A. H., and Sussman, J. L. (2003) EMBO Rep.4, 704-709) and have now solved the structure of Glc-Cerase conjugated with a...

Certificate-based encryption (CBE) combines traditional public-key encryption and certificateless encryption. However, it does suffer to the Denial of Decryption (DoD) attack called by Liu and Au. To capture this attack, they introduced a new paradigm called self-generated-certificate public key cryptography. In this paper we show that the problem of DoD attack can be solved with a new implicit...

BACKGROUND The effect of severity of screening result on delays to diagnosis has primarily been examined for mammographic abnormalities. This study will examine delays to assessment and diagnosis for women with an abnormal mammogram compared to women with an abnormal clinical breast examination (CBE) or abnormal CBE and mammogram. METHODS Using data routinely collected by Ontario Breast Scree...

Equilibrium stellar-dynamical systems are described by the time-independent Collisionless Boltzmann Equation (CBE). Two methods of building equilibrium stellar-dynamical systems are described. One begins by defining integrals of motion I1, I2, . . .; Jeans theorem implies that any function F = F(I1, I2, ...), is a solution of the time-independent CBE. Another begins by defining the mass distrib...

The purpose of this study was to evaluate whether screening by clinical breast examination (CBE) in addition to mammography affected participant satisfaction in the National Cancer Screening Program (NCSP). Data were derived from the Quality Evaluation of National Cancer Screening satisfaction survey. This population-based nationwide telephone survey included participants who had been screened ...

Abstract Light variability is an essential attribute of young stellar objects (YSOs) at the pre-main-sequence (PMS) stage, which can be treated as indicator to trace star formation. We present a statistical study on infrared NEOWISE new and large-sized PMS stars well Herbig Ae/Be (HAeBe) classical Be (CBe) identified from Gaia Data Release 2. A total 3792 (including 714 HAeBe), 417, 473 variabl...

PURPOSE To examine the effect of the type and the concentration of neutron capture agents on the values of compound biological effectiveness (CBE) in boron neutron capture therapy. METHODS AND MATERIALS After the subcutaneous administration of a (10) B-carrier, boronophenylalanine- (10) B (BPA) or sodium mercaptododecaborate- (10) B (BSH), at 3 separate concentrations, the (10) B concentratio...

BACKGROUND AND OBJECTIVES: Despite the implementation of screening guidelines to identify infants at risk for hyperbilirubinemia, chronic bilirubin encephalopathy (CBE) continues to be reported worldwide in otherwise healthy infants. The incidence of CBE in Canada is unknown. The objectives of this study were to establish the incidence of CBE in Canada and identify epidemiological and medical r...

background: breast cancer is the most common cancer in women. screening can reduce the rate of cancer and mortality. the aim of this study is description of screening programs about breast masses with clinical and para clinical examination. methods: this is a descriptive study on 952 women who had volunteered or were referred to tabriz behbood hospital during one-year period. data was collected...

BACKGROUND The effectiveness of clinic-based pulmonary rehabilitation in advanced COPD is well established, but few data exist for less severe patients treated in alternative settings. The purpose of this study was to investigate whether a novel, community-based exercise program (CBE) was feasible and effective for patients with moderate COPD. METHODS Nineteen patients with moderate COPD (mea...