BACKGROUND AND PURPOSE The age effect on the diffusion pattern in the basal ganglia differs from that in the white matter. The main purpose of our study was to provide further insight into the change of water diffusion in the basal ganglia during human brain aging by using the eigenvalues of DTI. MATERIALS AND METHODS We examined 71 healthy subjects (mean age, 41.8 +/- 14.5 years; age range, ...

In vivo voltammetry has been used to measure the release of dopamine evoked by electrical stimulation of the medial forebrain bundle (MFB). Simultaneous measurements have been made with voltammetric-sensing electrodes ipsilateral to the stimulating electrode in the nucleus accumbens and the caudate nucleus of the anesthetized rat. During the stimulation, the species observed in both regions is ...

OF PATHOLOGICAL FINDINGS Striatun, Subst. nigra Red nucleus Cerebellum Case 1 Numerical Hassler (1939) reduction of small cells in caudate and putamen Case 2 Reduction of Hassler (1939) small cells. Small softenings in caudate and putamen Case 3 Fibrillar gliosis Mylle and van in pallidum Bogaert (1940) Case 4 Atrophy of Mylle and van putamen and Bogaert ( 1948) caudate-6tat cribl6, small softe...

The caudate nucleus is commonly active when learning relationships between stimuli and responses or categories. Previous research has not differentiated between the contributions to learning in the caudate and its contributions to executive functions such as feedback processing. We used event-related functional magnetic resonance imaging while participants learned to categorize visual stimuli a...

IMPORTANCE Little is known about the relative contributions of multisystem degenerative processes across the spectrum of predemented cognitive decline in Parkinson disease (PD). OBJECTIVE To investigate the relative frequency of caudate nucleus dopaminergic and forebrain cholinergic deficits across a spectrum of cognitively impaired patients with PD to explore their relative, individual, and ...

We present a fully automatic diagnostic imaging test for Attention-Deficit/Hyperactivity Disorder diagnosis assistance based on previously found evidences of caudate nucleus volumetric abnormalities. The proposed method consists of different steps: a new automatic method for external and internal segmentation of caudate based on Machine Learning methodologies; the definition of a set of new vol...