The influenza A RNA polymerase possesses endonuclease activity to digest the host mRNA. Thus this endonuclease domain can be a target of anti-influenza A virus drug. Here we report that green tea catechins inhibit this viral endonuclease activity and that their galloyl group is important for their function. Docking simulations revealed that catechins with galloyl group fit well into the active ...

The influenza A RNA polymerase possesses endonuclease activity to digest the host mRNA. Thus this endonuclease domain can be a target of anti-influenza A virus drug. Here we report that green tea catechins inhibit this viral endonuclease activity and that their galloyl group is important for their function. Docking simulations revealed that catechins with galloyl group fit well into the active ...

(-)-Epicatechin (EC), (-)-epigallocatechin (EGC), (-)-epicatechin gallate (ECg), and (-)-epigallocatechin gallate (EGCg) were prepared from crude catechins (containing 90% cateehin in total) as described in our previous paper,i) Crude theaflavins, theafiavin (TFI), theaflavin monogallate A (TF2A), theafiavin monogallate B (TF2B), and theaflavin digallate (TF3) were prepared from black tea by ou...

Treatments for oral cancer may have significant adverse effect on the patient’s activities of daily living (ADL) and quality of life (QOL). However, foods may offer potential for chemoprevention. In recent years, attention has been focused on the anti-tumor and carcinogenesis-inhibiting actions of green tea. (−)Epigallocatechin-3-gallate (EGCG), the main component of green tea catechins, has be...

Knotweed rhizomes and young sprouts are used in a traditional Asian medicine. Because knotweed rhizomes contain large amount of stilbenes and catechins, the main objective of this study was analysis of selected phenolic compounds, including stilbenes and catechins, in young spring sprouts of the knotweed genus (Japanese knotweed (Reynoutria japonica), Giant knotweed (Reynoutria sachalinensis), ...

Tea leaf (Camellia sinensis) is rich in catechins, which endow tea with various health benefits. There are more than ten catechin compounds in tea, among which epigallocatechingallate (EGCG) is the most abundant. Epidemiological studies on the association between tea consumption and the risk of breast cancer were summarized, and the inhibitory effects of tea catechins on breast cancer, with EGC...

BACKGROUND Paliurus spina-christi Mill. (PS) fruits are widely used for different medical purposes in Turkey. Like in many medicinal herbs the studies concerning their activity, the activities of PS are also not well clarified. The aim of this study is to evaluate the antigenotoxicity of the compounds isolated and identified from the extracts of PS fruits. METHODS The active compounds were se...

The aim of the work was to determine main groups polyphenolic compounds in Quercus rubra L. raw materials.
 Materials and methods. leaves annual shoots Northern Red Oak used for research were collected August Lisnyky village Obuhiv district Kyiv Oblast (Ukraine). Determination component composition quantitative content flavonoids (including separately catechins), hydroxycinnamic acids, phe...