OBJECTIVES To estimate the prevalence of avoidable blindness in > or =50-year-olds in Nakuru district, Kenya, and to evaluate the Rapid Assessment for Avoidable Blindness (RAAB), a new methodology to measure the magnitude and causes of blindness. DESIGN Cross-sectional population-based survey. PARTICIPANTS Seventy-six clusters of 50 people 50 years or older were selected by probability prop...

purpose: to determine the incidence and risk factors associated with glaucoma following congenital cataract surgery (ccs) in children under age of 15 methods: this prospective cohort (since 2006) consisted of children less than 15 years of age who underwent cataract surgery with or without intraocular lens (iol) implantation. the role of the following factors on the development of glaucoma afte...

BACKGROUND The Italian-American Clinical Trial of Nutritional Supplements and Age-Related Cataract was designed to assess the impact of a multivitamin-mineral supplement on age-related cataract. Trial results showed evidence of a beneficial effect of the supplement on all types of cataract combined, opposite effects on two of the three types of cataract (beneficial for nuclear opacities and har...

PURPOSE To determine the current prevalence and causes of blindness in the Indian state of Andhra Pradesh to assess if blindness has decreased since the last survey of 1986-1989. METHODS A population-based epidemiology study, using a stratified, random, cluster, systematic sampling strategy, was conducted in the state of Andhra Pradesh in India. Participants of all ages (n = 10,293), 87.3% of...

Purpose: Age-related cataract is the leading cause of blindness worldwide. Variants in EPHA2 gene increase disease risk, and its knockout mice causes cataract. We investigated whether age, sex, genetic background, risk factors for age-related cataract, Epha2 genotype influence Epha2-related development mice. Methods: Cataract was monitored Epha2+/+, Epha2+/−, Epha2−/− (Epha2Gt(KST085)Byg) on C5...

Loss of transparency of the lens is termed cataract which is one of the commonest causes of blindness throughout the world. This major health problem appears to be much commoner in many developing countries such as India and Pakistan, where it causes visual disability at a substantially earlier age and several hypotheses have been put forward to explain this higher prevalence in these areas. Re...