Iota-carrageenan is a sulfated polysaccharide extracted from red seaweeds, which, formulated into nasal spray, has already been proven safe and effective in viral upper respiratory infections. In Calu-3, human epithelium cell line, we explored the activity of formula iota-carrageenan sodium chloride against SARS-CoV-2. this study, assayed formula, approved as spray for use, effectively inhibite...

Background: Gel-cream formulations used as cosmetics can present various textures. They may be fluid or semisolid, being highly influenced by their composition. These presentations require a complete study to obtain information about the physical stability and consistency of product possible interaction between its compounds. In this context, aimed develop cosmetic using carrageenan argan oil a...

Effect of Agar and kappa-Carrageenan on Thermal Mechanical Properties Thermo Plastic Starch (TPS) Thermoplastic starch needs to be blend with other materials because its limited properties. In order gain the desired properties, interaction between added component (filler, plasticizer, second polymer, etc) must concerned as it can affect performances final product. has been successfully made mix...

Kappa carrageenan was identified as a possible gel for melting-triggered release at 30–40 °C with the inclusion of non-ionic surfactant use in detergency or food-related applications. The formulation kappa (0.6–3% w/w) and either Tween 20 Dehypon LS 36: two different surfactants (0–5% w/w). Rheology micro differential scanning calorimetry (µDSC) found that addition had significant increase gell...

BACKGROUND Non-steroidal anti-inflammatory agents (NSAIDs), steroids and representatives of other pharmacological groups [1, 2] are widely used for pharmacological regulation of inflammation. However, their anti-inflammatory effects are accompanied by serious adverse reactions [3, 4]. There was a hope that newer NSAIDs, selective inhibitors of COX-2, would be safer, but their longer-term use ap...

Although theophylline has been suggested to have an anti-inflammatory effect, there have been few reports to show the in vivo effect and the mechanism of anti-inflammatory activity of theophylline experimentally. To reveal the anti-inflammatory activity of theophylline, we studied the effect of theophylline and its metabolites on carrageenan-induced edema in rat foot pad. Subcutaneous injection...

The study aimed at analyzing the role of each of interleukin-1 (IL-1 ) and Nitric Oxide (NO) in development of peripheral acute inflammation in mice in presence/absence of a one hour pre-administered acetylsalicylic acid (ASA). Eighty male mice were utilized. Carrageenan was administered intraplanterly (0.05 ml of 0.5, 1 or 2%, W/V). The examined parameters were paw volume, IL-1 and nitrite lev...

Aqueous, ethanolic and methanolic extracts of Ruta graveolens were investigated for anti-inflammatory activity in carrageenan induced paw edema in wistar male rats, and compared to a positive control drug, Voveran. These extracts were given (ip) in a concentration of 20 and 50 mg/kg b.w. before carrageenan injection. Methanolic extracts of R. graveolens with a concentration of 20 mg/kg b.w. and...