We measured the degree of association between obesity, blood pressure, insulin resistance, and insulin secretion in 72 male and female obese hypertensive, obese nonhypertensive, and normal weight control subjects. Baseline weight, body mass index, percent body fat, waist/hip ratio, and systolic and diastolic blood pressures were obtained. Insulin sensitivity was assessed according to Bergman's ...

In recent years, adverse effects of obesity on female reproduction and male fertility have received significant attention. In this study, we investigated infertility improvements following L-Carnitine treatment using a high-fat diet (HFD)-induced obesity mouse model. Five-week-old male mice were divided into a control diet (CTD) group, a HFD group, and a HFD with L-Carnitine supplementation (HF...

In mammals, during the aging process, an atrophy of the muscle fibers, an increase in body fat mass, and a decrease in skeletal muscle oxidative capacities occur. Compounds and activities that interact with lipid oxidative metabolism may be useful in limiting damages that occur in aging muscle. In this study, we evaluated the effect of L-carnitine and physical exercise on several parameters rel...

Half-marathon running is of high popularity. Recent studies tried to find predictor variables for half-marathon race time for recreational female and male runners and to present equations to predict race time. The actual equations included running speed during training for both women and men as training variable but midaxillary skinfold for women and body mass index for men as anthropometric va...

PURPOSE Numerous dietary factors elevate serum levels of insulin and insulin-like growth factor I (IGF-I), both potent prostate cancer mitogens. We tested whether varying dietary carbohydrate and fat, without energy restriction relative to comparison diets, would slow tumor growth and reduce serum insulin, IGF-I, and other molecular mediators of prostate cancer in a xenograft model. EXPERIMEN...

OBJECTIVE The purpose of this study was to determine the effect of body fat distribution on plasma lipid and lipoprotein concentrations in healthy individuals. METHODS Subjects were 290 women and 223 men aged 20-66 years old. Lipid panels were obtained and truncal adiposity measurements were determined by total body dual energy x-ray absorptiometry (DXA). Physical activity was measured using ...