Whether lean body mass (LBM) composition, especially skeletal muscle and abdominal organs, differs in adults with type 2 diabetes (T2DM) compared with nondiabetic healthy controls has not been investigated. A subset of African-American and Caucasian participants with T2DM from the Look AHEAD (Action for Health in Diabetes) trial had body composition assessed and compared with a sample of health...

Muscle ring finger-1 (MuRF1) is a muscle-specific E3 ubiquitin ligase that has been implicated in the regulation of cardiac mass through its control of the ubiquitin proteasome system. While it has been suggested that MuRF1 is required for cardiac atrophy, a resting cardiac phenotype has not been reported in mice with a null deletion [knockout (KO)] of MuRF1. Here, we report that MuRF1 KO mice ...

a 47-year-old man presented as a dyspnea and fatigue. a transthoracic echocardi-ography (tte) performed to assess valvar heart disease and left ventricular (lv) function showed a large hydatid cysts in the inter ventricular septum bulging to posterior of heart and compressing its overlying muscle as whitish round mass. the patient underwent elective surgery by evacuation of septal hydatid cysts...

Hiatus hernia is a common medical condition. An elderly woman being investigated for dyspnoea of unknown aetiology had a transthoracic echocardiogram as part of her investigations. This alarmingly demonstrated a large left atrial mass. Further assessment with cardiac magnetic resonance imaging revealed a large hiatus hernia compressing the left atrium and no intra-cardiac mass. The case succinc...

Background We previously showed that leg lean mass Z-score (LLMZ) correlates with metabolic exercise performance in Fontan patients. However, the mechanism by which leg lean mass influences exercise is not clear since LLMZ does not correlate with ventricular function or cardiac output at rest. We hypothesized that LLMZ would correlate with cardiac output at exercise and the change in cardiac ou...

UNLABELLED Cardiac hemangiomas are extremely rare, and account for 5-10% of benign cardiac tumors. Most clinical presentations involve patient dyspnea on exertion and arrhythmia; asymptomatic patients are uncommon. A 45-year-old man had an asymptomatic left ventricular mass that was found incidentally during an echocardiogram. Magnetic resonance images showed an isointense protruding mass attac...

Primary cardiac lymphoma is a very rare form of lymphoma primarily or mainly involving the heart, as in the two cases presented in this report. Various imaging modalities, including coronary computed tomography angiography, cardiac magnetic resonance imaging and positron emission tomography were useful for the characterization and diagnosis of cardiac mass. Pathologic confirmation was successfu...