نتایج جستجو برای: carbopol
تعداد نتایج: 639 فیلتر نتایج به سال:
Gamma-oryzanol merupakan senyawa antioksidan alami yang diperoleh dari minyak dedak padi atau lebih dikenal dengan rice bran oil (RBO). diketahui dapat melindungi kulit radiasi ultraviolet dan meningkatkan kelembaban kulit, sehingga dimanfaatkan sebagai antikerut pelembab di bidang kosmetik. Terdapat dua komponen penting menentukan sifat fisik emulgel, yaitu emulgator gelling agent. Penelitian ...
objective (s): mucoadhesive disc is one of the various routes of drug delivery for curing buccal disease.materials and methods:everydiscs containing 70 mg stem bark extract of ziziphus jujuba were formulated by using carbopol 934, pvp k30 and gelatin as polymers. discs were made by granulation and direct compression. discs were standardized based on the total phenol. properties such as in vi...
Bawang Putih (Allium sativum L.) memiliki banyak manfaat bagi kesehatan tubuh, diantaranya sebagai antibakteri dan antifungi. putih antifungi masih digunakan secara tradisional, sehingga perlu dilakukan formulasi. Gel dipilih untuk formulasi bawang karena tidak lengket, stabil, mempunyai estetika yang bagus. Dalam gel ekstrak etanol diperlukan basis Na-CMC Carbopol menjaga stabilitas gel. Penel...
Aim: The aim of the work was to explore mucoadhesive properties Mastic gum by involving it in microspheres with Amoxicillin Trihydrate as a model drug. Using Carbopol-934P and varying amounts gum. Methods: 9 interpretations were made using Design expert software. A central composite design applied test impact independent variables (Carbopol-934P mastic levels) on drug released at 10h strength r...
The aim of our study was to develop a liposomal carrier system for the local treatment of bacterial vaginosis, capable to efficiently deliver entrapped drug during an extended period of time. Chloramphenicol was entrapped in liposomes composed of egg phosphatidylcholine/egg phosphatidylgycerol-sodium (9:1, molar ratio) and prepared by two different methods, the proliposome method and the polyol...
PURPOSE The purpose of this study was to develop and evaluate metronidazole loaded floating-mucoadhesive microsphere for sustained drug release at the gastric mucosa. METHODS Alginate gastroretentive microspheres containing metronidazole were prepared by ionic gelation method using sodium bicarbonate as gas forming agent, guar gum as mucoadhesive polymer, and Eudragit L100 as drug release mod...
The present study outlines a systematic approach for designing and development of Ofloxacin floating tablets to enhance the bioavailability and therapeutic efficacy of the drug. Floating tablets of Ofloxacin have shown controlled release thereby proper duration of action at a particular site and are designed to prolong the gastric residence time after oral administration. Floating tablets of Of...
The objective of this work was to develop an oral mucosal drug delivery system to facilitate the local and systemic delivery of acyclovir for the treatment of oral herpes infection caused by the herpes simplex virus (HSV). An in situ gelling system was used to increase the residence time and thus the bioavailability of acyclovir in oral mucosa. Temperature and pH trigged in situ gel formulation...
Article history: Received on: 12/10/2012 Revised on: 27/10/2012 Accepted on: 03/11/2012 Available online: 29/11/2012 Mini matrices containing Losartan potassium as a model drug were prepared by extrusion method using Hydroxy propyl methyl cellulose as matrix materials with or without xanthan gum and carbopol, and combination of xanthan gum and carbopol and propylene glycol as plasticizer. The p...
Chewable modified release tablets containing two active ingredients vitamin C (200mg) and Sodium Fluoride (2mg) were formulated for the treatment of dental diseases. Other ingredients include Mannitol, Carbopol and Hydroxyl-Propyl Methylcellulose (HPMC), in different ratios. These tablets were prepared by direct mixing of Hydroxypropyl Methylcellulose (HPMC), vitamin C, Sodium Fluoride, Carbopo...
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