• In the microcirculation of the renal cortex, fluid exchange proceeds at very high rates in two anatomically and functionally distinct capillary systems, the glomerular and the peritubular capil-laries. Net ultrafiltration is confined to the glomeru-lus, which consists of a tuft of capillaries surrounded by the ultrafiltrate enclosed within Bowman's capsule at the proximal end of the nephron. ...

1N T GENERAL, previous investigators have concluded that the capillary permeability to proteins is either normal or increased in patients with congestive failure." I t is difficult to reconcile such results with the consistent finding of increased plasma volume in congestive heart failure. In a previous study of normal individuals, iodinated serum albumin was used to measure the transcapillary ...

We used plethysmograph techniques to measure or calculate the tissue and capillary forces and flows (capillary pressure, tissue and plasma oncotic pressure, transcapillary pressure drop, lymph flow, and interstitial pressure) in a dog hindpaw preparation in situ at three different venous pressures (PV). Since lymph was flowing from the preparation, an isovolumetric state represented an isofiltr...

Cardiovascular disease remains the leading cause of death worldwide(1). Cardiac tissue engineering holds much promise to deliver groundbreaking medical discoveries with the aims of developing functional tissues for cardiac regeneration as well as in vitro screening assays. However, the ability to create high-fidelity models of heart tissue has proven difficult. The heart's extracellular matrix ...

Augmentation of viability random pattern flaps has long been an issue in plastic surgery. Up to date no agents were clinically introduced. Atorvastatins are used for lipid lowering. They also effective on flap survival with their angiogenic, anti-inflammatory, antioxidant effects systeic administration. In this study, Atorvastatin is topically alleviation Mc Farlane rats. Wibstar albino type 20...

1) Measured during spontaneous breathing in ten patients with diffuse interstitial lung disease, total pulmonary resistance averaged 3.53 +/- 1.56 cm H(2)O per L per second; airway resistance, 1.63 +/- 0.79 cm H(2)O per L per second; and lung tissue resistance, 1.90 +/- 0.95 cm H(2)O per L per second (range, 0.89 to 3.96). The lung tissue resistance was on an average about four times higher in ...

Most oxygen required to support the energy needs of vertebrate tissues is delivered by diffusion from microvessels. The presence of red blood cells (RBCs) makes blood flow in the microcirculation highly heterogeneous. Additionally, flow regulation mechanisms dynamically respond to changes in tissue energy demand. These spatiotemporal variations directly affect the supply of oxygen to parenchyma...

introduction: klippel–trenaunay syndrome (kts) is a rare congenital mesodermal abnormality characterized by varicose veins, cutaneous capillary malformation, as well as bone and soft tissue hypertrophy. case report: a 2-week-old female infant presented to our clinic because of vascular nevus and progressive enlargement of her right extremities and trunk since birth. the patient was treated with...

The aim of this study was to describe quantitatively changes in the coronary capillary network resulting from hypertrophy in spontaneously hypertensive rats (SHR) and a potential effect of long-term treatment of these animals with nifedipine. Age-matched male SHR and Wistar-Kyoto (WKY) rats were treated for 27 weeks. Four experimental groups were analyzed: (1) untreated SHR, (2) nifedipine-trea...