Several cases of Candida bloodstream infections were documented from June to October 2004 at a tertiary care center in Bogotá, Colombia. Since no cases of candidemia had occurred during the preceding four months, an outbreak was declared. As a result, a microbiological study, a revision of infection control practices and a case-control study were performed. In all, 18 cases of candidemia were a...

The purpose of this study was to determine among patients with candidemia the real rate of ophthalmoscopy and the impact of performing ocular assessment on the outcome of the disease. We performed a post hoc analysis of a prospective, multicenter, population-based candidemia surveillance program implemented in Spain during 2010-2011 (CANDIPOP). Ophthalmoscopy was performed in only 168 of the 36...

background candida species are normal microflora of  oral cavity, vagina, and gastrointestinal  tract. they are the third most prevalent cause of pediatric health care–associated  bloodstream fungal infection. this study aimed to provide an epidemiological feature of candidiasis and also presents an antifungal susceptibility profile of clinical candida isolates among children. materials and met...

BACKGROUND Statins have immunomodulatory properties and hinder Candida growth. However, it is unknown whether they may improve prognosis in patients with candidemia. We sought to determine the effect of prior statin use on the clinical outcomes of patients suffering candidemia. METHODS AND FINDINGS Multicenter cohort study of hospitalized adults with candidemia between 2005 and 2011 in six ho...

Abstract Background: Candidemia is the main cause of fungal nosocomial bloodstream infections and is related to meaningful mortality specially, in pediatrics. Mortality rate range from 5% to 71%, and it can reach as high as 81%. Delays in beginning of treatment have also been linked to intensified mortality. The epidemiology of Candida infection is changing from region to region. Regiona...

Background: In the recent years, there has been a significant rise in invasive candida infections. Epidemiological studies have demonstrated shift trend of Candida species being isolated and their susceptibility patterns. The present study was carried out to evaluate single institution experience burden candidemia. Methods: This prospective among 48 isolates from blood urine samples patients ho...

INTRODUCTION Anidulafungin is a new echinocandin antifungal agent with indications for use in esophageal candidiasis and candidemia. The mortality and morbidity associated with fungal infections in healthcare facilities necessitates the development of new treatment options for these diseases. AIMS This review assesses the pharmacology and evidence for the use of anidulafungin in the treatment...