نتایج جستجو برای: ca mey ex dc schbip
تعداد نتایج: 235828 فیلتر نتایج به سال:
The identification of the specific DC subsets providing a critical role in presenting influenza antigens to naïve T cell precursors remains contentious and under considerable debate. Here we show that CD8(+) T lymphocyte (TCD8+) responses are severely hampered in C57BL/6 mice deficient in the transcription factor Batf3 after intranasal challenge with influenza A virus (IAV). This transcription ...
Amaç: Bu çal??mada, alt? orkide türünün yumrusundaki mineral besin elementi (N, P, K, Ca, Mg, S, Fe, Cu, Zn, Mn ve B) a??r metal (Co, Cr, Ni Cd) seviyeleri standart analitik metotlar kullan?larak belirlenmi?tir.Materyal Yöntem: çal??mada bitki materyali olarak Orchis purpurea Huds. subsp. purpurea, provincialis Balb. ex Lam.& DC., coriophora L. coriophora, Ophrys oestifera M. Bieb. oest...
Cell therapy with lymphocytes is an attractive approach for cancer immunotherapy. Methods to generate ex vivo effector cells directed against whole autologous tumor antigens are under investigation. Our procedure involved stimulation of autologous lymphocytes with antigen-pulsed dendritic cells (DC). Experimental conditions were established with DC, matured with TNFa, LPS and CD40L, from health...
Current treatments for rheumatoid arthritis (RA) do not reverse underlying aberrant immune function. A genetic predisposition to RA, such as HLA-DR4 positivity, indicates that dendritic cells (DC) are of crucial importance to pathogenesis by activating auto-reactive lymphocytes. Here we show that microRNA-34a provides homoeostatic control of CD1c+ DC activation via regulation of tyrosine kinase...
Our studies show that at low illuminance, close to the light compensation point, plants of all studied species ( Plectranthus amboinicus (Lour.) Spreng, Rhoicissus rhomboidea (E. Mey. ex Harv.) Planch., Elettaria cardamomum (L.) Maton) have a smaller total leaves area and decorative qualities, they not antimicrobial activity. Plants grown under illuminance from 500 2000 lux, depending on specie...
Dendritic cell (DC)-based immunotherapy employs the patients' immune system to fight neoplastic lesions spread over the entire body. This makes it an important therapy option for patients suffering from metastatic melanoma, which is often resistant to chemotherapy. However, conventional cellular vaccination approaches, based on monocyte-derived DCs (moDCs), only achieved modest response rates d...
Conventional dendritic cells (cDC) are ex vivo differentiated professional antigen presenting cells capable of potently stimulating naïve T cells and with vast potential for immunotherapeutic applications. The manufacture of clinical-grade cDC is relatively complex and requires several days for completion. Clinical trials showed poor trafficking of cDC from subcutaneous injection sites to lymph...
Chlamydia trachomatis, an obligate intracellular bacterial pathogen of mucosal surfaces, is a major cause of preventable blindness and sexually transmitted diseases for which vaccines are badly needed. Despite considerable effort, antichlamydial vaccines have proven to be elusive using conventional immunization strategies. We report the use of murine bone marrow-derived dendritic cells (DC) pul...
Abstract Funding Acknowledgements Type of funding sources: None. Background Apical sparing (AS) is an useful marker cardiac amyloidosis (CA). However, this pattern can also be found in other conditions that lead to left ventricular hypertrophy (LVI), like hypertension (HT) or hypertropic cardiomyopathy (HCM). We aimed assess the AS at rest and exercise patients with CA LVI-no CA. hypothesize ma...
The lack of available tumor antigens with strong immunogenicity, human leukocyte antigen restriction, and immunosuppression via regulatory T-cells (Tregs) and myeloid-derived suppressor cells are limitations for dendritic cell (DC)-based immunotherapy in patients with advanced head and neck cancer (HNC). We sought to overcome these limitations and induce effective antitumor immunity in the host...
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