نتایج جستجو برای: c6

تعداد نتایج: 6449  

2016
Xin-hua Zhang Ning-ning Zhang Xian-bing Meng Yang Zhang Yun Qian Yun-jie Xie

Hesperetin is a plant flavonoid known for its anti-oxidant and anti-cancer properties. The effect of hesperetin treatment on cerebrally implanted C6 glioma cells in rats was studied. C6 tumours were implanted in rats (n=20). The animals with C6 gliomas were treated with hesperetin (10 and 20 mg/kg/ day). Tumour weight, survival of animals, regional tumour permeability analysis was performed. Mo...

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 2007
Valeria Ramaglia Rosalind Helen Mary King Michelle Nourallah Ruud Wolterman Rosalein de Jonge Marja Ramkema Miriam Ann Vigar Sandra van der Wetering Brian Paul Morgan Dirk Troost Frank Baas

The complement (C) system plays an important role in myelin breakdown during Wallerian degeneration (WD). The pathway and mechanism involved are, however, not clear. In a crush injury model of the sciatic nerve, we show that C6, necessary for the assembly of the membrane attack complex (MAC), is essential for rapid WD. At 3 d after injury, pronounced WD occurred in wild-type animals, whereas th...

2002
Shirzad Jenab

OBJECTIVES: The purpose of this study was to compare the effects of neurotrophic cytokines on the JAK/STAT transcription factors and the immediate early gene, c-fos, in C6 glioma cells and in primary astrocyte cultures. METHODS: In this study we compared the effects of interleukin 6, leukemia inhibitory factor and interferon gamma on C6 glioma cells and on primary astrocyte cultures using elect...

2010
Aaron Taylor Lee Ayse L. Lee-Robinson

BACKGROUND Medial epicondylitis, or golfer's/pitcher's elbow, develops as a result of medial stress overload on the flexor muscles at the elbow and presents as pain at the medial epicondyle. Cervical radiculopathy has been associated with lateral epicondylitis, but few associations between the cervical spine and medial epicondylitis have been made. Researchers propose that there is an associati...

Journal: :Cancer research 1994
V R Amberger P A Paganetti H Seulberger J A Eldering M E Schwab

C6 rat glioblastoma cells are able to attach to and to spread on culture dishes which are coated with purified central nervous system myelin, in contrast to normal astrocytes, fibroblasts or neurons which adhere poorly and are unable to spread on this substrate. The metalloprotease blockers o-phenanthroline and a newly developed oligopeptide could specifically inhibit C6 cell spreading on centr...

2010
Doug E. Brackney Jaclyn C. Scott Fumihiko Sagawa Jimmy E. Woodward Neil A. Miller Faye D. Schilkey Joann Mudge Jeffrey Wilusz Ken E. Olson Carol D. Blair Gregory D. Ebel

Mosquitoes rely on RNA interference (RNAi) as their primary defense against viral infections. To this end, the combination of RNAi and invertebrate cell culture systems has become an invaluable tool in studying virus-vector interactions. Nevertheless, a recent study failed to detect an active RNAi response to West Nile virus (WNV) infection in C6/36 (Aedes albopictus) cells, a mosquito cell lin...

Journal: :Journal of Synthetic Organic Chemistry, Japan 1986

2013
Lei-qing Li Fang Shen Xiao-yan Xu Hong Zhang Xiao-feng Yang Wei-guo Liu

Although the combination of herpes simplex virus type 1 (HSV-1) thymidine kinase (TK) with ganciclovir (GCV) has been shown as a promising suicide gene treatment strategy for glioma, the almost immunodepressive dose of GCV required for its adequate in vivo efficacy has hampered its further clinical application. Therefore, In order to reduce the GCV dose required, we aim to compare the therapeut...

Journal: :The Journal of chemical physics 2009
Tomasz Kuś Victor F Lotrich Rodney J Bartlett

The equation-of-motion coupled-cluster singles and doubles (EOM-CCSD) method has been implemented into the massively parallel ACES III program using two alternative strategies: (1) storing the entire EOM Hamiltonian matrix prior to diagonalization and (2) recomputing the four-virtual part of the matrix from integrals in a direct mode. The second is found to be far more efficient. EOM-CC shows v...

Journal: :Indian journal of experimental biology 2011
Nidhi Sharma Veena Garg

Treatment of diabetic mice with glibenclamide and crude extract (BE) significantly declined the FBG content. However, amongst the 6 isolated compounds, 3 compounds (C1, C4 and C6) appreciably subsided the exaggerated level of FBG. Simultaneously, glibenclamide, BE, C4 and C6 treatment markedly enhanced the hepatic glycogen content as compared to diabetic control group. Administration of crude e...

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