Various 6-aralkyl-9-substituted-6H-indolo[2,3-b]quinoxalines were synthesized by reaction of 1,5-disubstituted 2,3-dioxo-2,3-dihydroindole and orthophenylene diamine. Appreciable anticancer activity of compounds 5b, 5d, 5g and 5l at various cell lines among 59 human tumor cell panels was observed. All the synthesized compounds were evaluated for cytostatic activity against human Molt 4/C8 and C...

The effects of loading rate on the reinforced concrete beams are experimentally studied in the present paper. Firstly, the effects of strain rate on the different grades of concrete are investigated using the electro-hydraulic servo-controlled testing system at the strain rate that might be experienced during earthquakes. Based on the test results, the dynamic increasing factors (DIF) of concre...

We present the regression-based Monte Carlo simulation algorithms for solving the stochastic control models associated with pricing and hedging of the Guaranteed Lifelong Withdrawal Benefit (GLWB) in variable annuities, where the dynamics of the underlying fund value is assumed to evolve according to the stochastic volatility model. The GLWB offers a lifelong withdrawal benefit even when the po...

We apply a logistic smooth transition market model (LSTM) to a sample of returns on Australian industry portfolios to investigate whether bull and bear market betas differ. Unlike other studies, our LSTM model allows for smooth transition between bull and bear states and allows the data to determine the threshold value. The estimated value of the smoothness parameter was very large for all indu...

Binary events are involved in many economic decision problems. In recent years, considerable progress has been made in diverse disciplines in developing models for forecasting binary outcomes. We distinguish between two types of forecasts for binary events that are generally obtained as the output of regression models: probability forecasts and point forecasts. We summarize specification, estim...

A novel method for quantum reactive scattering calculations is introduced and tested for simple model problems. It is shown to be efficient and quite accurate. The method is based on a simple modification to the time independent Schrödinger equation, (H2E)C50. It is obtained by setting (H2E)C5B where B is a localized boundary inhomogeneity. A necessary and sufficient number of arbitrary linearl...

Abstract. The article examines integration of cryptocurrencies as electronic payment systems in e-commerce enterprises. Practical usage Ethereum and Bitcoin systems, well factors that may affect their functionality are studied. Coinbase Commerce Bitpay, market leaders cryptocurrency providers, were analyzed to compare issues commission analysis with traditional LiqPay, PayPal. It is determined ...

Bu çalışma kapsamında farklı sonlu elemanlar yaklaşımları kullanılarak on katlı betonarme bir binanın radye temel kalınlıkları ve beton sınıfları değişiminin oturma üzerine etkisi araştırılmıştır. İlk yaklaşımda yapı düşey yükleri, sistemi alan yükü olarak etkitilmiştir. İkinci ise zemin birlikte modellenerek üst yükleri zemine doğrudan aktarılmıştır. İki yaklaşımla elde edilen modellerde 80-10...

this study examined the effects of implanted cortisol (to imitate chronic stress) on the hematological responses and cortisol values of female great sturgeon, huso huso, after an endoscopic operation. at the beginning of experiment, all the fish were examined using an endoscope to evaluate gonad development. then, in order to mimic chronic stress following surgery, capsules of cocoa?? butter co...

The dihydroxy C(50)-carotenoid, decaprenoxanthin, was produced by Aureobacterium sp. collected from sea water. The addition of D-psicose to the culture medium improved the growth of cells and the yield of the carotenoid. The (13)C-NMR spectrum of decaprenoxanthin, which has not previously been reported, was successfully measured.