The RNA silencing pathway constitutes a defence mechanism highly conserved in eukaryotes, especially in plants, where the underlying working principle relies on the repressive action triggered by the intracellular presence of double-stranded RNAs. This immune system performs a post-transcriptional suppression of aberrant mRNAs or viral RNAs by small interfering RNAs (siRNAs) that are directed t...

Since the attack runs on the Security Manager layer, it can reuse a lot of the existing network stack that is already in place for this approach. This namely concerns everything bellow HCI [1]. Actually, the whole procedure starting with the authentication bypass and continuing to data injection (which would be a regular communication anyway) can be done using a general Bluetooth 4.0 Smart Read...

Sequential bypassing agents may be a safe and effective treatment during major orthopedic surgery in hemophilia patients with inhibitors.

Positive phase III results for Roche’s emicizumab in haemophilia A published in The New England Journal of Medicine ● HAVEN 1 showed emicizumab reduced bleed rate by 87% compared with on-demand bypassing agents ● All 12 secondary endpoints in HAVEN 1 were positive, including an intra-patient comparison that showed emicizumab reduced bleed rate by 79% compared to prior prophylactic bypassing age...

Headland sediment bypassing connects short-term physical forcing and long-term morphological response. The contributions from King et al., 2021, https://doi.org/10.1029/2020JC017053 are a substantial step in understanding the complexities by combining field observations, process-based numerical modeling, empirical generalization with development of an improved parametrization headland bypassing...