BACKGROUND Burn injury results in a chronic inflammatory, hypermetabolic, and hypercatabolic state persisting long after initial injury and wound healing. Burn survivors experience a profound and prolonged loss of lean body mass, fat mass, and bone mineral density, associated with significant morbidity and reduced quality of life. Understanding the mechanisms responsible is essential for develo...

T he natural history of serious burns is characterized by burn shock, which is usually lethal to those with large burns during the first few postinjury days, burn wound sepsis, which commonly kills those who survive burn shock during the first few postinjury weeks, and postburn deformity in those who survive to heal their wounds by contraction and epithelialization. Each of these issues has bee...

The authors Jeschke et al. (2015) have collected an impressive dataset describing pathophysiological reactions to burns in elderly versus adult burn patients. The leading observationwas that elderly burn patients experience ahighermortality rate thanadults or children. Furthermore,whereas mortality rates were reduced for other age categories, outcome for elderly patients did not improve much ov...

BACKGROUND Burned patients are usually resistant to the neuromuscular effects of nondepolarizing relaxants, mostly because of receptor changes. The magnitude of the resistance is related to burn size and time after burn. Mivacurium is a muscle relaxant, degraded by plasma cholinesterase, whose enzyme activity is decreased in burns. The present study tested the hypothesis that burn-induced depre...

background : burn wounds are one of the health problems in modern societies that are associated with irreparable harms and many side problems for patients and their families. infection due to burn wounds is the main cause of death in such patients. one of the methods to prevent infection of burn wounds is topical antibiotic ointments. this study aimed to investigate and identify effective ointm...

Global optimization of transport aircraft is performed to minimize fuel burn for a specified mission. The design space includes the geometry, wing airfoils, primary structure, engine size and cycle parameters, and the flight profile parameters. The method employs a number of physics-based models for structural sizing and weight estimation, viscous CFD for all major aerodynamic components, and a...

Burn patients may suffer both physical and psychopathological consequences and their quality of life and the presence of psychopathological symptoms should be evaluated. The Burn Specific Health Scale - Brief (BHSH-B) is a tried and tested instrument for assessing burn patients' quality of life. The aim of this study is to propose the Italian translation of BSHS-B and presents the preliminary r...

Little is known about the effect of massage on post-burn tissue in children. We conducted a pilot study to examine the effect of massage (3-5 days) on mood and range of motion (ROM) in eight post-burn children. Participants showed significant increases in ROM from Time 1 (pre-massage, first day) to Time 2 (post-massage, last day) in massaged tissue but not control (non-massaged) tissue. Mood wa...

This study prospectively examined the incidence and severity of large joint contractures after burn injury and determined predictors of contracture development. Data were collected prospectively from 1993 to 2002 for consecutive adult burn survivors admitted to a regional burn center. Demographic and medical data were collected on each subject. The primary outcome measures included the presence...

background self-inflicted burn injuries carry considerable mortality and morbidity among otherwise fit young individuals. this study assessed the epidemiologic pattern and outcome of these injuries in a burn care facility in pakistan. methods the study was carried out at pakistan institute of medical sciences (pims) burn care centre in islamabad over a period of 2 years. it included all adult p...