Background: The differential diagnosis of Burkitt lymphoma/leukemia (BL) and the double or triple hit lymphomas remains often problematic in terms immunophenotyping association with MYC gene analysis. In past, BL-like B-cell malignancy precursor phenotype (BCP-ALL) was described. Case Report: We report here an 84-year-old male massive ascites without superficial lymphadenopathy. Abdominal parac...

AIMS Fine needle aspiration (FNA) cytology is an accepted means of diagnosing and typing common forms of lymphoma, particularly small lymphocytic lymphoma, follicular lymphoma, and large B cell lymphoma. However, its usefulness for diagnosing less common forms of lymphoma is not clearly established and this study was designed to examine this. METHODS The study reviewed the FNAs of suspected l...

Hepatitis C virus (HCV) and hepatitis B virus (HBV) have been associated with hematopoietic malignancies, but data for many subtypes are limited. From the U.S. Surveillance, Epidemiology, and End Results-Medicare database, we selected 61,464 cases (> or = 67 years) with hematopoietic malignancies and 122,531 population-based controls, frequency-matched by gender, age, and year (1993--2002). Log...

The transcription factor KLF4 may act both as an oncogene and a tumor suppressor in a tissue-depending manner. In Tand pre-B-cell lymphoma, KLF4 was found to act as tumor suppressor. We found the KLF4 promoter methylated in B-cell lymphoma cell lines and in primary cases of B-cell lymphomas, namely, follicular lymphoma, diffuse large B-cell lymphoma, Burkitt lymphoma, and in classic Hodgkin lym...

Toothache of a lower primary molar followed by bilateral swelling of the lower molar regions were the first symptoms of a 6-year-old Finnish male with Burkitt-type malignant lymphoma. Radiographic examination revealed osteolytic changes in the right mandibular and left maxillary quadrant. The cortical bone around the affected teeth was absent and some teeth were grossly displaced. When the ther...

Discordant lymphoma is rare condition in which different types of malignant lymphomas occurring in different anatomic sites. The two diseases may present clinically as concurrent or sequential disease (10). Herein we are reporting a Pakistani female in her 60s, a carrier of hepatitis B virus with multiple comorbidities presented with cervical lymphadenopathy, diagnosed as Hodgkin's lymphoma, mi...