The disease phenotype of bovine spongiform encephalopathy (BSE) and the molecular/ biological properties of its prion strain, including the host range and the characteristics of BSE-related disorders, have been extensively studied since its discovery in 1986. In recent years, systematic testing of the brains of cattle coming to slaughter resulted in the identification of at least two atypical f...

Distinct prion strains often exhibit different incubation periods and patterns of neuropathological lesions. Strain characteristics are generally retained upon intraspecies transmission, but may change on transmission to another species. We investigated the inactivation of two related prions strains: BSE prions from cattle and mouse-passaged BSE prions, termed 301V. Inactivation was manipulated...

PURPOSE/OBJECTIVES To examine health beliefs and sociodemographic and breast cancer-related variables influencing breast self-examination (BSE) practice. DESIGN Descriptive, cross-sectional. SETTING Two vocational training centers in Istanbul, Turkey. SAMPLE 438 women were selected using a convenience sampling method. Participants had not had breast cancer and were not currently pregnant ...

BACKGROUND The bovine spongiform encephalopathy (BSE) epidemic presented homogeneity of the phenotype. This classical BSE (called C-type) was probably due to the contamination of the food chain by a single prion strain. However, due to the active surveillance and better techniques, two rare variants of BSE have been recently reported in different continents without a clear correlation to the BS...

INTRODUCTION Scrapie and bovine spongiform encephalopathy (BSE) are transmissible spongiform encephalopathies (TSEs) which naturally affect small and large ruminants respectively. However, small ruminants, which are susceptible to BSE under experimental conditions, have been exposed to the same or similar contaminated food additives as cattle. To date two natural cases of BSE in small ruminants...

Melanoma is recognized as one of the most aggressive cancers with a relatively high propensity for metastasis. The prognosis of melanoma remains poor in spite of treatment advances, emphasizing the importance of additional preventive measures. Isoflavonoids have become not only potential chemopreventive, but also important therapeutic natural agents. We evaluated the antiproliferative and proap...

BACKGROUND The aim of this study was to determine beliefs concerning breast self-examination in first- and second-degree relatives of patients with breast cancer and evaluate their breast self-examination (BSE) application. MATERIALS AND METHODS A survey study was conducted in an oncology polyclinic and general surgery clinic of a hospital in Ankara, the capital of Turkey with a sample of 140...

A qqq BSE formalism based on an input 4-fermion Lagrangian of ‘current’ u, d quarks interacting pairwise via a gluon-exchange-like propagator in its nonperturbative regime, is employed for the construction of a relativistic qqq-wave function under the Covariant Instantaneity Ansatz (CIA). The chiral invariance of the input Lagrangian is automatically ensured by the vector character of the gluon...

BACKGROUND Classical bovine spongiform encephalopathy (BSE) is an acquired prion disease of cattle. The bovine prion gene (PRNP) contains regions of both high and low linkage disequilibrium (LD) that appear to be conserved across Bos taurus populations. The region of high LD, which spans the promoter and part of intron 2, contains polymorphic loci that have been associated with classical BSE st...

The correct name for Mad Cow Disease is Bovine Spongiform Encephalopathy (BSE) and I will use this abbreviation throughout the text. BSE was first detected in England in 1985. Since then millions of cattle have been slaughtered either because they were infected or for precautionary measures. Payment for compensation to the farmers has cost the UK Government some Euro 6 billion. Although the UK ...