Bromelain is a mixture of proteolytic enzymes that extracted primarily from pineapples. It present in almost all the aerial parts plant—the peels, leaves, stems and fruit—although only fruit contain significant amounts. The market-demand for bromelain quickly increasing, especially health sector as it can be used drug and/or nutraceutical. Although complete molecular mechanism has not been full...

Oral administration of hydrolytic enzymes (HE), such as bromelain, trypsin and rutosid, may have beneficial effects on the clinical course of neurological symptoms related to multiple sclerosis (MS). This is supported by a complete protection by HE from experimental allergic encephalomyelitis, an animal model related to MS. Three hundred and one patients with relapsing MS were enrolled in a dou...

After preliminary assays, with papain, bromelain and ficin, on a range of citrulline p-nitroanilides, values of Km and kcat. for the papain-catalysed hydrolysis of three derivatives, N alpha- benzyloxycarbonylcitrulline p-nitroanilide, benzyloxycarbonylphenylalanylcitrulline p-nitroanilide and benzyloxycarbonylglycylphenylalanylcitrulline p-nitroanilide, were obtained. It is concluded that benz...

Background: Bromelain (BL) is an enzyme extracted from Ananas comosus, which has been known for its therapeutic properties. Objectives: The anticarcinogenic activity of BL was examined with and without the presence magnetic carbon nanotubes (MCNTs) against HT-29 colorectal cancer cells. Methods: operational factors affecting adsorption, such as contact time (30, 60, 90, 120, 180 min), adsorbent...