Organic LEDs that emit light in the short-wavelength infrared (SWIR) region, which spans 1–2 ?m are attractive for applications biosensors, biomedical imaging and spectroscopy, surveillance. However, fabrication of such devices with high radiance has not yet been achieved owing to an intrinsic limitation imposed by energy-gap law, leads extremely low emission efficiencies. Here, we report accep...

The use of optical sensing for in vivo applications is compelling, since it offers the advantages non-invasiveness, non-ionizing radiation, and real-time monitoring. However, signal-to-noise ratio (SNR) signal deteriorates dramatically as biological tissue increases. Although increasing laser power can improve SNR, intense lasers severely disturb processes viability. Quantum with bright squeeze...

The symptoms of jet lag cause distress to an increasing number of travelers. Potentially they may impair sleep, mood and cognitive performance. Critically timed exposure to bright light and melatonin administration can help to reduce symptoms. Bright light is one of the most powerful synchronizers of human rhythms and melatonin serves as a "dark pulse" helping to induce nighttime behaviors. Thu...

BACKGROUND The phase and amplitude of rhythms in physiology and behavior are generated by circadian oscillators and entrained to the 24-h day by exposure to the light-dark cycle and feedback from the sleep-wake cycle. The extent to which the phase and amplitude of multiple rhythms are similarly affected during altered timing of light exposure and the sleep-wake cycle has not been fully characte...

The addition of two 3-h periods of very dim light, one before and one after a normal 8-h photoperiod, advances sexual maturity in pullets by about a week. This trial tested the hypothesis that dim light given before a short day of normal intensity is linked to form a more stimulatory day length and that dim light given after it is photosexually ignored. Pullets were reared from 2 d of age on 8-...

Background: Bright white light has been successfully used for the treatment of depression. There is interest in identifying which spectral colors of light are the most efficient in the treatment of depression. It is theorized that green light could decrease the intensity duration of exposure needed. Late Wake Treatment (LWT), sleep deprivation for the last half of one night, is associated with ...

Light falling on the retina is converted into an electrical signal which stimulates serotonin synthesis. Previous studies described an increase of plasma and CNS serotonin levels after bright light exposure. Ghrelin and leptin are peptide hormones which are involved in the regulation of hunger/satiety and are related to serotonin. Neopterin and kynurenine are immunological markers which are als...