نتایج جستجو برای: breast cancer cell line
تعداد نتایج: 2671475 فیلتر نتایج به سال:
background: the adjuvanticity potential of lactobacillus casei was first suggested in an old survey. the present study was designed to investigate the efficacy of a new immunotherapy against breast cancer made by mixing an extract of heated 4t1 mammary carcinoma cell line and a heat-killed preparation of lactobacillus casei. methods: female balb/c mice (6–8 weeks old, n=40) were challenged subc...
The p21 belongs to the CIP/KIP family of CDK inhibitors involved in cell cycle arrest at specific stages of the cell cycle progression. DNA methylation is the best studied epigenetic mark that have been evidently associated to chromatin condensation, and repression of gene transcription. The CpG island hypermethylation in promoter region of certain genes occurs in cancer cells and affects tumor...
abstract boswellia has been widely used in traditional medicine for the treatment of different diseases such as cancer in iran. the aim of this study was to evaluate the effect of the gum methanol extract of boswellia thurifera on the viability and p53 gene expression of cultured breast cancer cells. the gum methanol extract was obtained in various concentrations using the maceration method. no...
cancer is the second leading cause of death in the world. despite advances in the diagnosis and treatment, overall survival of patients still remains poor. hence, there is an urgent need for development of new anticancer agents. considering promising biological activity of 1,3,4-thiadiazole derivatives, in the present study, synthesis and cytotoxicity assessment of new derivatives of this ring ...
background: adipose tissue has characteristics of an endocrine organ which releases a number of adipocyte-specific factors, known as adipocytokines. it has recently suggested that adipocytokines might play a role in pathogenesis and progression of certain cancers, especially in gastric cancer. this study has managed to investigate endogenous and/or exogenous expression of visfatin and resisti...
background: mehr-80 is a newly established adherent human large cell lung cancer cell line that has not been transfected until now. this study aims to define the optimal transfection conditions and effects of some critical elements for enhancing gene delivery to this cell line by utilizing different non-viral transfection procedures. methods: in the current study, calcium phosphate (cap), deae-...
Introduction: Studies have shown that plant compounds have significant anticancer effects that if the challenges of using them are resolved, Can be the successor to the synthetic compounds commonly used in cancer therapy. Therefore, in this study, the liposomal nano- carriers containing Nepeta persica extract have been investigated in order to improve the physicochemical characteristics and eva...
Introduction: Breast cancer is regarded as one of the most common female cancers in the world. Many efforts have been made to treat the breast cancer, among which surgery, radiation, and chemotherapy can be mentioned. There is an increasing interest regarding using herbal preparations as a promising source of new anti-cancer drugs because of their safety profile and efficient pharmaceutical pot...
Abstract: Background and Aim: Breast cancer is the most common cancer among women. Given that plant compounds have been used to treat cancer for centuries. Despite some reports of antitumor effects on some species of this genus, the anticancer activity of Stachys setifera has not yet been reported. The aim of this study was to investigate the cytotoxic effect of hydroalcoholic extract of Stachy...
objective(s):berberine, a naturally occurring isoquinoline alkaloid, has shown antitumor properties in some in vitro systems. but the effect of berberine on breast cancer has not yet been completely studied. in this study, we evaluated anticancer properties of berberine in comparison to doxorubicin. materials and methods: the antiproliferative effects of berberine and doxorubicin alone and in c...
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