The 2021 World Health Organization (WHO) classification of brain tumors,[1] as a follow-up to the 2016 update, incorporates validated molecular markers previously established histomorphological features and has led significant shift in diagnosis management adult diffuse gliomas. provides distinction between astrocytoma Isocitrate Dehydrogenase (IDH) mutant grade 4 IDH-wildtype glioblastoma, whi...

Introduction Oligodendrogliomas represent 5-18% of all intracranial gliomas. They arise in the cortex and white matter of cerebral hemispheres. The majority of oligodendrogliomas are low grade tumors. Based on their clinical representation oligodendrogliomas can not be easily distinguished from other brain tumors especially astrocytomas. As the treatment is different in between oligodendrogliom...

BACKGROUND Outcomes projects can be a catalyst for determining disease- and treatment-related consequences for patients with rare tumors. The Adult Ependymoma Outcomes (AEO) survey uses self-reported experience to evaluate how this tumor affects patient groups throughout the illness trajectory. METHODS Patients completed the AEO survey via a Web-based portal. The survey included questions on ...

PURPOSE To determine the maximum tolerated dose of single fraction radiosurgery in patients with recurrent previously irradiated primary brain tumors and brain metastases. METHODS AND MATERIALS Adults with cerebral or cerebellar solitary non-brainstem tumors </= 40 mm in maximum diameter were eligible. Initial radiosurgical doses were 18 Gy for tumors </= 20 mm, 15 Gy for those 21-30 mm, and ...

BACKGROUND AND PURPOSE We investigated the relationship between tumor blood-flow measurement based on perfusion imaging by arterial spin-labeling (ASL-PI) and histopathologic findings in brain tumors. MATERIALS AND METHODS We used ASL-PI to examine 35 patients with brain tumors, including 11 gliomas, 9 meningiomas, 9 schwannomas, 1 diffuse large B-cell lymphoma, 4 hemangioblastomas, and 1 met...

PURPOSE To compare thallium-201 single-photon emission CT with conventional CT in grading the malignancy of gliomas and to determine the reliability of each in tumor assessment. METHODS We studied 37 patients who had gliomas (31 high grade and 6 low grade) and compared the CT findings with the thallium-201 index, which we defined as tumor uptake relative to the uptake in the contralateral hem...

BACKGROUND AND PURPOSE MR fingerprinting allows rapid simultaneous quantification of T1 and T2 relaxation times. This study assessed the utility of MR fingerprinting in differentiating common types of adult intra-axial brain tumors. MATERIALS AND METHODS MR fingerprinting acquisition was performed in 31 patients with untreated intra-axial brain tumors: 17 glioblastomas, 6 World Health Organiz...

Computer-Aided Diagnosis (CAD) is in wide practice in clinical work for the detection and prognosis of various types of abnormalities. For this, medical images acquired in various tests by utilizing diverse imaging modalities are used. In medical imaging, detecting and classifying the brain tumors in Magnetic Resonance Image (MRI) is a demanding and critical task. MRI gives anatomical structure...

INTRODUCTION Current MRI sequences are limited in identifying brain areas at risk for high grade glioma recurrence. We employed intraoperative 3-Tesla functional MRI to assess cerebrovascular reactivity (CVR) after high-grade glioma resection and analyzed regional CVR responses in areas of tumor recurrence on clinical follow-up imaging. METHODS Five subjects with high-grade glioma that underw...