نتایج جستجو برای: brain site

تعداد نتایج: 813198  

Journal: :Journal of biophotonics 2010
Steen J Madsen Henry Hirschberg

The blood-brain barrier (BBB) poses a significant impediment for the delivery of therapeutic drugs into the brain. This is particularly problematic for the treatment of malignant gliomas which are characterized by diffuse infiltration of tumor cells into normal brain where they are protected by a patent BBB. Selective disruption of the BBB, followed by administration of anti-cancer agents, repr...

2017
San-Gang Wu Wen-Wen Zhang Zhen-Yu He Jia-Yuan Sun Yong-Xiong Chen Ling Guo

Background There are few population-based studies of the sites of distant metastasis (DM) and survival from esophageal cancer (EC). The aim of this study was to assess the patterns and survival outcomes for site-specific DM from EC using a population-based approach. Methods Patients diagnosed with de novo stage IV EC between 2010 and 2014 were identified from the Surveillance, Epidemiology, a...

Journal: :Brain : a journal of neurology 2006
Krista L Hyde Robert J Zatorre Timothy D Griffiths Jason P Lerch Isabelle Peretz

Congenital amusia (or tone deafness) is a lifelong disability that prevents otherwise normal-functioning individuals from developing basic musical skills. Behavioural evidence indicates that congenital amusia is due to a severe deficit in pitch processing, but very little is known about the neural correlates of this condition. The objective of the present study was to investigate the structural...

Journal: :Neuro-Signals 2013
Arulmani Manavalan Manisha Mishra Siu Kwan Sze Klaus Heese

p60 transcription regulator protein (p60TRP) facilitates the processing of the amyloid precursor protein towards the non-amyloidogenic pathway by inhibiting the β-secretase action. This protein was initially identified to be downregulated in the temporal lobe of brains from Alzheimer's disease patients. p60TRP is one of the G-protein-coupled receptor (GPCR)-associated proteins which directly in...

Journal: :Sleep 2023

Abstract Introduction Machine Learning (ML) can draw upon complex patient data to predict current and future health status, but the best performing ML models are often difficult interpret. One such ML-defined marker is brain age index (BAI), difference between ML-predicted chronological (CA) using electroencephalogram (EEG) during sleep. BAI associated with multiple disease states including inc...

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