This study evaluated the relationship between the location of the most severe coronary artery stenosis and the subsequent acute myocardial infarction (AMI). Methods: Of 1590 patients who were admitted with a diagnosis of AMI, we identified 44 patients who had undergone previous myocardial perfusion SPECT. Thirty-one of these patients also had previous coronary angiography. The relationshi...

Introduction and Objective: To investigate perfusion in dementia and Parkinson’s disease (PD) we performed Tc-HMPAO brain SPECT with semiquantitative analysis of Brodmann areas in different aged patients. Materials and Methods: We retrospectively evaluated 104 patients, 30 with Alzheimer’s disease (AD), 26 with frontotemporal dementia (FTD), 25 with mild cognitive impairment (MCI), 23 with PD, ...

Brain imaging has progressed from exclusion of rare treatable mass lesions to a specific antemortem diagnosis. MR imaging-derived hippocampal atrophy and WMH are regarded as imaging biomarkers of AD and CVD respectively. Abnormal FP-CIT SPECT or cardiac iodobenzamide SPECT is a useful supportive imaging feature in the diagnosis of DLB. Frontal and/or anterior temporal atrophy and anterior defec...

A 67 years old woman was referred to nuclear medicine center for myocardial perfusion imaging (MPI) for assessment of ischemic heart dieses (IHD).She had a history of atypical chest pain and dyspnea since about 10 days before admission. The MPI SPECT/CT was performed by stress/redistribution Tl-201 protocol. MPI was interpreted as relatively good coronary flow with no appreciable stress induced...

BACKGROUND Most olfactory testings are subjective and since they depend upon the patients' response, they are prone to false positive results. The aim of this study was to use quantitative brain perfusion SPECT in order to detect possible areas of brain activation in response to odorant stimulation in patients with post-traumatic impaired smell in comparison to a group of normal subjects. MET...

we report an unusual case of hemimegalencephaly (hmg) associated with ipsilateral congenital-infiltrating lipomatosis of the face in a five-month-old boy. hemimegalencephaly is a rare but unique malformation characterized by enlargement of all or parts of a cerebral hemisphere. the affected hemisphere may have focal or diffuse neuronal migration defects, with areas of polymicrogyria, pachygyria...

BACKGROUND AND PURPOSE Cyclosporin has neurotoxic effects in a significant number of transplant patients that are associated with characteristic findings on MR images. Focal abnormalities in cerebral perfusion have been implicated in the pathophysiology of cyclosporin neurotoxicity. In the clinically asymptomatic patient, however, it is not known whether any imaging evidence of cyclosporin's ef...

We will discuss clinical and radiological findings of a woman who attempted suicide by hanging. We report a 19-year-old women attempted suicide by hanging herself. There was no known period of global brain ischemia. She had a score of 7 on the Glasgow coma scale. CT scan showed bitemporal hippocampal atrophy and SPECT showed non-activated area on right temporal and temporo-occipital regions. Th...

BACKGROUND Recently, modifications of Aβ1-42 levels in CSF and plasma associated with improvement in memory and language functions have been observed in patients with mild-moderate Alzheimer's disease (AD) treated with plasma exchange (PE) with albumin replacement. OBJECTIVE To detect structural and functional brain changes in PE-treated AD patients as part of a Phase II clinical trial. MET...