نتایج جستجو برای: brain ischemic tolerance

تعداد نتایج: 665014  

Journal: :Neuroscience 2014
M C X Pinto F Simão F L P da Costa D V Rosa M J N de Paiva R R Resende M A Romano-Silva M V Gomez R S Gomez

Brain ischemic tolerance is an endogenous protective mechanism activated by a preconditioning stimulus that is closely related to N-methyl-d-aspartate receptor (NMDAR). Glycine transporter type 1 (GlyT-1) inhibitors potentiate NMDAR and suggest an alternative strategy for brain preconditioning. The aim of this work was to evaluate the effects of brain preconditioning induced by sarcosine, a Gly...

Journal: :مجله علوم اعصاب شفای خاتم 0
nafise bahrami a. islamic azad university, mashhad branch, mashhad, iran b. member of mashhad neuroscience research group of islamic azad university, mashhad branch, mashhad, iran zahra ghane a. islamic azad university, mashhad branch, mashhad, iran b. member of mashhad neuroscience research group of islamic azad university, mashhad branch, mashhad, iran hasan abbassian neuroscience department, mashhad university of medical sciences, mashhad, iran

introduction: there are several different molecular pathways in tissue damage by ischemic brain injury. the use of antioxidants and free radical scavengers are a matter of attention by some researchers. crocus sativus (saffron) is used previously for protective effects in ischemia state by some researchers. to assess pathologic aspects of neuroprotection of saffron in some susceptible brain are...

Aim: Oxidative stress plays a crucial role in the pathophysiology of ischemic stroke. Since water-solublefullerene derivatives act as the potent scavenger of oxygen free radicals in biological systems, we aimedto investigate the possible protective effects of fullerol nanoparticles on brain infarction and edema intransient model of focal cerebral ischemia in rat.Materials & Methods: Experiment ...

Background & Aims: According to the recent studies, fullerene nanoparticles have a potent scavenging property for free radicals in biological environments. Since reactive oxygen species (ROS) is a fundamental mechanism of brain damage in stroke, we aimed to evaluate the neuroprotective effects of fullerene nanoparticles on ischemia-induced brain injuries in experimental model of stroke...

Journal: :Stroke 2004
Susanne Wegener Barbara Gottschalk Verica Jovanovic René Knab Jochen B Fiebach Peter D Schellinger Thomas Kucinski Gerhard J Jungehülsing Peter Brunecker Bianca Müller Anna Banasik Nicola Amberger Klaus D Wernecke Mario Siebler Joachim Röther Arno Villringer Markus Weih

BACKGROUND AND PURPOSE We investigated whether transient ischemic attacks (TIAs) before stroke can induce tolerance by raising the threshold of tissue vulnerability in the human brain. METHODS Sixty-five patients with first-ever ischemic territorial stroke received diffusion- and perfusion-weighted MRI within 12 hours of symptom onset. Epidemiological and clinical data, lesion volumes in T2, ...

Journal: :Expert Review of Cardiovascular Therapy 2009

Journal: :World Journal of Cardiovascular Diseases 2015

باغبانیان, سیدمحمد, رمضانی, منیره, عابدینی, محمود, یزدانی چراتی, جمشید,

Background and purpose: Ischemic brain stroke is one of the most common neurologic diseases and the second cause of death among adults. There is currently no information on the relationship between risk factors influencing anterior and posterior circulation. The most common ischemic strokes occur in the (anterior circulation) AC, while strokes occurring in the posterior circulation (PC) are...

حیدریان, اسفندیار, ربیعی, زهرا, رفیعیان کوپایی, محمود,

Background and Objective: Clinically significant changes in central nervous system (CNS) function are observed following brief periods of CNS blood flow interruption. Stroke patients exhibit cognitive, emotional, and electrophysiological changes during the recovery phase. Lavender belongs to the Labiatae family and is used for a variety of cosmetic and therapeutic purposes in herbal medicine. T...

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