BACKGROUND Ultrasonographic assessments of intima-media thickness and plaques in the carotid artery are widely used as surrogate markers for coronary atherosclerosis, but prospective evaluations are scarce and appear to be lacking in patients with coronary artery disease. Ultrasonographic evaluations of femoral vascular changes have not been studied prospectively. METHODS AND RESULTS In the A...

OBJECTIVE With increasing interest in the role of non-traditional lipid risk factors in coronary artery disease, we undertook this study to relate LDL subclass size and carotid intima-media thickness of the common carotid artery in coronary artery disease patients. METHODS The study was conducted in 106 patients during their first visit (study group I) and after 12 months (study group II). In...

BACKGROUND The present study was designed to characterize early structural changes of large arteries in renal transplant recipients with no clinical evidence of cardiovascular disease and normal blood pressure values, and to analyse the relationship between arterial alterations and those of the heart. METHODS Intima media thickness and atherosclerotic plaques of the carotid arteries as well a...

BACKGROUND Epidemiologic studies have suggested that a high phytoestrogen intake is inversely associated with cardiovascular disease risk factors and the incidence of cardiovascular events. However, the relation between the intake of isoflavone, a major component of phytoestrogen, and vascular endothelial function and the atherosclerotic burden remains unclear. OBJECTIVE We aimed to investiga...

BACKGROUND The metabolic syndrome is associated with increased vascular disease risk. We evaluated two carotid ultrasound measurements, namely intima media thickness and total plaque volume, in a Canadian Oji-Cree population with a high metabolic syndrome prevalence rate. METHODS As part of the Sandy Lake Complications Prevalence and Risk Factor Study, 166 Oji-Cree subjects (baseline metaboli...

The center of the pandemic of diabetes is the lifethreatening cardiovascular complications that can be categorized into macrovasculopathy, microvasculopathy, and diabetic cardiomyopathy. Macrovasculopathy affects large vessels and manifests as atherosclerosis and the subsequent coronary artery disease, peripheral artery disease, and cerebrovascular disease. Atherosclerosis and its related compl...

Objective: A magnesium deficiency is known to be involved in many abnormalities in the post-menopausal women. Previous studies proposed that magnesium (Mg) might prevent atherosclerosis. In this study the efficacy of serum magnesium level and its relation with carotid intima media thickness (CIMT) in post-menopausal women was evaluated. Methods: Eighty Iranian Postmenopausal women were included...

INTRODUCTION    According to the "common soil" hypothesis, diabetic microangiopathy and macroangiopathy have a similar pathophysiological background. It has been well documented that carotid artery atherosclerosis in patients with type 2 diabetes is associated with cardiovascular complications; however, it remains unclear whether there is a similar association for microvascular complications. O...

Atherosclerosis is a condition where the arteries become narrowed and hardened because of excessive build up of fatty substances called plaques around the artery wall. The disease disrupts the flow of blood around the body resulting in serious cardiovascular complications. The Intima Media thickness (IMT) is used as a validated measure for the evaluation of atherosclerosis. Manual assessment of...