drug design is generally achieved through trial and error methods, which is a time and resource consuming process and novel methods are needed to improve it. mathematical modelling is one of the possible solutions to speed up this process. in this study, we have presented box-jenkins model, to predict the vasorelaxant activity (pec50) of a set of benzopyrane compounds. we used the hyperchem sof...

Within the nucleus, pre-mRNA molecules are complexed with a set of proteins to form heterogeneous nuclear ribonucleoprotein complexes. A1, an abundant RNA binding protein present in these complexes, has been shown to bind selectively to single-stranded RNAs and destabilize base-pairing interactions. In this study.A1 is shown to promote the rate of annealing of complementary RNA strands greater ...

grape is used in large amounts and different types (fresh, raisin, vinegar, molasses, juice, unriped grape and etc). remarkable amount also are preserved in stores and cold-rooms to be supplied out of season, that causes  quality and weight decrease. this research was conducted to study different factors which affect the grape shelf-life. obtaining more information about optimum conditions and ...

In this paper we discuss the solution of the clustering problem usually solved by the K-means algorithm. The problem is known to have local minimum solutions.A simulated annealing algorithm for the clustering problem. The solution of the clustering problem usually solved by the K-means algorithm.In this paper, we explore the applicability of simulated annealing. Clustering problem is investigat...

We investigate the effect of annealing temperature on self-assembled Au droplets on Si (111). The annealing temperature is systematically varied while fixing other growth parameters such as deposition amount and annealing duration clearly to observe the annealing temperature effect. Self-assembled Au droplets are fabricated by annealing from 50°C to 850°C with 2-nm Au deposition for 30 s. With ...

Understanding of the mechanisms of annealing twin formation is fundamental for grain boundary engineering. In this work, the formation of annealing twins in a 304L austenitic stainless steel is examined in relation to the thermo-mechanical history. The behavior of annealing twins of various morphologies is analyzed using an in-situ annealing device and EBSD. The results confirm that there is a ...

We study adiabatic reverse annealing (ARA) in an open system. In the closed system (unitary) setting, this protocol allows avoidance of first-order quantum phase transitions selected models, resulting exponential speedup compared with standard annealing, provided that initial state algorithm is close Hamming distance to target one. Here, we show decoherence can significantly modify conclusion: ...

The formation of nano/ultrafine grained ferrite in low carbon steels containing different amounts of niobium was investigated using thermomechanical treatment which consisted of annealing of 85% cold rolled martensite with different parameters. The specimens were characterized by optical and scanning electron microscopy and Vickers hardness test. A lamellar dislocation cell structure was formed...

In the current study, the recrystallization behavior of 75% cold-rolled Fe-22Mn-10Al-1.4C steel during annealing at 750, 770, 790, 810, and 830°C was studied. X-ray diffraction patterns and optical microscopy were used to characterize microstructures. The Vickers Micro-hardness test was used to characterize recrystallization kinetics during annealing. Johnson-Mehl-Avrami-Kolmogorov (JMAK) model...

OVERVIEW: There is an increased demand for the production of nextgeneration super-high-speed and low-power-consumption CMOS (complementary metal-oxide semiconductor) devices using SOI (silicon on insulator). Major global device manufacturers are actively commercializing this product. In SOI technology, a device is fabricated in a silicon layer (SOI layer) formed on a BOX (buried oxide) film. Al...