The apparent number, n, of water ligands coordinated to bound Mn(I1) in the ternary arginine kinase-MnADP or ATP complexes, in the abortive quatemary complex E-MnADParginine and in the transition state analog complex formed by addition of nitrate to the quatemary complex was estimated from the frequency dependence of the longitudinal proton relaxation rate of water (PRR) of lobster (Homarus ame...

We present a simple exact analytical solution, using the Weyl-Titchmarsh-Kodaira spectral theorem, for the spectral function of the one-dimensional diatomic molecule model consisting of two attractive delta function wells in the presence of a static external electric field. For sufficiently deep and far apart wells, this molecule supports both an even and an odd state, and the introduction of a...

The structure of the type III variant of chloramphenicol acetyltransferase reveals that Thr-174, a conserved residue, is hydrogen-bonded to a bound water molecule (water 252). Modeling studies (P. C. E. Moody and A. G. W. Leslie, unpublished data) suggested that water 252 could play a part in transition state stabilization via a hydrogen bond to the oxyanion of the putative tetrahedral intermed...

It is shown that the resonance reported by Szmytkowski and Szmytkowski [Phys. Lett. A 235 (1997) 217] is not a proximity resonance as defined by Heller [Phys. Rev. Lett. 77 (1996) 4122]. Rather, it can be related to a threshold resonance connected to the antisymmetric bound state of the two wells, which enters the continuum when the wells are one scattering length apart. In addition, a surprisi...

Since September 11, 2001, protecting the nation’s water infrastructure and improving water network resiliency have become priorities in the water industry. In this work, we develop methods to mitigate the consequences of water shortage resulting from destruction of facilities in water networks. These methods integrate search techniques, such as branch-and-bound and genetic algorithms, with a hy...

Ensuring an adequate supply of clean water is an urgent global issue. In 1992, the United Nations (UN) designated March 22 of every year as World Water Day (WWD) to increase awareness of the importance of clean water conservation. Also, Population Action International (PAI) has reported a shortage of fresh water in developing and under-developed countries. The demand for clean water will contin...

To elucidate the role of zinc-bound water in liver alcohol dehydrogenase catalysis, chelation by 1,lO-phenanthroline and 2.2-bipyridine was studied. The rate constants for association of both chelating agents to the active center zinc were pH-dependent with a pK, of 9.2 and preferential binding to a protonated form. The binary complex dissociation rate constants were pHindependent for both chel...

We propose an extension of applicability of the Rayleigh-Schrödinger perturbation expansions. Our innovated prescription employs an N−parametric re-normalization of wavefunctions and is shown to be still able to define the corrections via an N by N matrix inversion. For the first few positive integers N , the piecewise constant forces with N discontinuities are recommended as a promising and ne...

In an effort to define the nature of desiccation tolerance, a comparison of the water sorption characteristics was made between tissues that were resistant and tissues that were sensitive to desiccation. Water sorption isotherms were constructed for germinated and ungerminated soybean axes and also for fronds of several species of Polypodium with varying tolerance to dehydration. The strength...

The microwave dielectric properties of perfluorosulfonic acid membranes are characterized by a two-port transmission line technique. Two dielectric relaxation modes are observed in the microwave region (0.045–26 GHz) at 25°C. The higher frequency process observed is identified as the cooperative relaxation of bulk-like water, whose amount was found to increase linearly with water content in the...