BACKGROUND DNA adenine methylation plays an important role in several critical bacterial processes including mismatch repair, the timing of DNA replication and the transcriptional control of gene expression. The dependence of bacterial virulence on DNA adenine methyltransferase (Dam) has led to the proposal that selective Dam inhibitors might function as broad spectrum antibiotics. METHODOLOG...

This paper applies the tool of social impact assessment (SIA) to understand the effects of large dam projects on human communities. We draw upon data from two recent SIA projects: the Lesotho Highlands Water Project in Southern Africa, and the Manwan Dam, located on the upper Mekong River in southwestern China. These two cases allow us to examine the social impacts of large dam projects through...

At present, more and more attentions have been paid to dam risk management around the world. In order to deal with the fuzziness and randomness of dam failure, the cloud model was introduced into the risk assessment of dam failure, which was combined with Analytic Hierarchy Process(AHP) method and fuzzy theory, and then the multilevel fuzzy comprehensive assessment of dam failure risk was reali...

Today Environmental Impact Assessment (EIA) is known as one of the most important tools for decision makers in the construction of civil and industrial projects towards sustainable development. In the past, projects were evaluated based on cost and benefit analysis regardless of the physical and biological environmental effects and its socio-economical impacts. According to the Department of En...

The temporal migration patterns of European glass eel Anguilla anguilla at the Couesnon estuarine dam (Mont-Saint-Michel Bay, France) were examined in winter and spring 2004 and 2005. The dam which is located close to the river mouth constitutes a major obstacle for upstreammigrating glass eels. The migration was observed at different temporal scales, from within individual tides to complete ti...

Whether or not the excitation-contraction (E-C) uncoupler diacetyl monoxime (DAM) and cytochalacin D (Cyto D) alter the ventricular fibrillation (VF) activation patterns is unclear. We recorded single cell action potentials and performed optical mapping in isolated perfused swine right ventricles (RV) at different concentrations of DAM and Cyto D. Increasing the concentration of DAM results in ...

We have examined the presence of methylated adenine at GATC sequences (Dam phenotype) in the DNA of 23 eubacteria and 13 archaebacteria by using isoshizomer restriction enzymes. We have found a completely Dam+ phenotype in bacteria of nine genera related to the families Enterobacteriaceae, Parvobacteriaceae, and Vibrionaceae, and in the five cyanobacteria tested. We have found a partial Dam+ ph...

Synopsis The failure of landslide dam formed by mass movements may occur by sudden sliding of the dam body. So, this study focuses on three-dimensional (3D) transient seepage and slope stability analysis of landslide dam. The 3D slope stability model coupled with transient seepage flow model is used for numerical simulations. Experiments are performed in the flume to measure movement of moistur...

After some initial trials with RCC the first 3 RCC dams were constructed almost simultaneously. The Zaaihoek Dam and De Mistkraal Weir were designed and constructed by DWAF while the Arabie Dam, now called Flag Boshielo Dam, was designed by a consultant and constructed by a contractor for the then Leboa Homeland Government. The latter, a composite dam with a concrete spillway and an embankment ...

The main purpose of the dam is to control the surface streams and rivers across the country. Dam construction and formation of river and big water reservoirs and resources happen in the glen is a big incident which would change its surrounding area considerably. In fact, constructing a dam the glen width is close and fishes don't migrate from upstream to downstream and ultimately it would led t...