Software component architectures allow assembly of applications from individual software modules based on clearly defined programming interfaces, thus improving the reuse of existing solutions and simplifying application development. Furthermore, the plug-in programming paradigm additionally enables runtime reconfigurability, making it possible to adapt to changing application needs, such as di...

Spamato is an extendable, collaborative spam filter system written in Java that combines different filter technologies to provide more accurate results. This thesis takes Spamato a big step further by introducing a plug-in architecture. Users and developers can now customize their system by adding, updating, and removing plug-ins. The underlying plug-in architecture is completely independent of...

Proteins are translocated across membranes through a channel that is formed by the prokaryotic SecY or eukaryotic Sec61 complex. The crystal structure of the SecY channel from M. jannaschii revealed a plug domain that appears to seal the channel in its closed state. However, the role of the plug remains unclear, particularly because plug deletion mutants in S. cerevisiae are functional. Here, w...

Background: Dental extraction can initiate a sequence of biological events that may lead to an insufficient bone volume, which compromise implant placement. To minimize loss, alveolar ridge preservation procedures were developed. However, smoking has been shown adversely affect the outcomes procedures. Hence, this clinical study aimed assess ability platelet-rich fibrin maintain volume and its ...

Problem Statement: The evolution of software is made difficult by the need to integrate new features with all previously implemented features in software applications. Approach: present study introduced a general-purpose, platform-independent object-oriented design metric plug-in framework called jmetric intended to help building scalable, extendable object-oriented design metric plug-ins. jmet...

Secure fixation of bone-patellar tendon-bone grafts is essential to allow early joint mobilization after anterior cruciate ligament (ACL) reconstruction surgery. This study was designed to evaluate four fixation methods of patellar tendon-bone grafts in cadaveric knees. Fifty-one fresh cadaveric patellar tendon-bone specimens were anchored in tibial or femoral metaphyseal bone tunnels. Group I ...

This paper proposes plug-in bandwidth selection for kernel density estimation with discrete data via minimization of mean summed square error. Simulation results show that the plug-in bandwidths perform well, relative to cross-validated bandwidths, in non-uniform designs. We further find that plug-in bandwidths are relatively small. Several empirical examples show that the plug-in bandwidths ar...