Nonunion is uncommon after proximal humerus fracture surgery. There is no agreement about preferred method of treatment. Traditional approaches have included laterally based locking plates, autogenous grafting, and endosteal support to provide improved biomechanical stability. Open reduction and internal fixation (ORIF) of proximal humeral nonunion has been performed with various methods, inclu...

Fetuin-A / α2-Heremans-Schmid-glycoprotein (gene name Ahsg) is a systemic inhibitor of ectopic calcification. Due to its high affinity for calcium phosphate, fetuin-A is highly abundant in mineralized bone matrix. Foreshortened femora in fetuin-A-deficient Ahsg-/- mice indicated a role for fetuin-A in bone formation. We studied early postnatal bone development in fetuin-A-deficient mice and dis...

Nonunion and secondary reduction loss complicate open distal femur fractures with bone loss. The authors hypothesized that locking plates decrease subsequent bone grafting yet maintain alignment and immediate postfixation radiographic features predict primary union. A retrospective chart/radiographic review was performed at a Level 1 university trauma center. Thirty-four adults with 36 open AO/...

PURPOSE Biomechanical comparison of straight DCP and helical plates for fixation of transversal and oblique tibial bone fractures were analyzed and compared to each other by axial compression, bending and torsion tests. METHOD An in vitro osteosynthesis of transverse (TF) and oblique bone fracture (OF) fixations have been analysed on fresh sheep tibias by using the DCP and helical compression...

The unique and complex anatomy of the orbit requires significant contouring of the implants to restore the proper anatomy. Fractures of the orbital region have an incidence of 10-25% from the total facial fractures and the most common age group was the third decade of life. The majority of cases required reconstruction of the orbital floor to support the globe position and restore the shape of ...

Femur fractures are often treated by fixing metallic bone plates in the fractured area. But subjected to stress shielding. To overcome shielding, a material with similar strength and stiffness that of human can be better suited. The present study focuses on fabrication carbon-flax/bioepoxy hybrid composite. femur plate was modeled using SOLIDWORKS ® 2020 3D modeling software package. Hybrid com...

objective: dendritic cells (dcs) are the most effective antigen-presenting cells with many applications. however, dcs can be generated in vitro by various methods from bone marrow cells, each with varying pros and cons. thus, we evaluated three different methods to generate dcs from mice bone marrow cells. materials and methods: bm cells from c57bl/6 mice were cultured in the presence of 1000 u...

Solute delivery to avascular cartilaginous plates is critical to bone elongation, and impaired transport of nutrients and growth factors in cartilage matrix could underlie many skeletal abnormalities. Advances in imaging technology have revolutionized our ability to visualize growth plates in vivo, but quantitative methods are still needed. We developed analytical standards for measuring solute...

Background and purpose: Transverse problems in the maxilla (high arched- narrow hard plates) can cause respiratory disorders. Palatal expansion can be helpful in this way. The present study aimed at evaluating the effect of bone borne expansion and tooth borne palatal expansion on airway volume. Materials and methods: A review study was performed by search in Google Scholar, Scopus, PubMed, Em...

BACKGROUND Humeral nonunion that persists through various unsuccessful attempts at management, presents a real challenge. When combined with severe osteoporosis in elderly patients, the problems only increase. This study aims to investigate the best option for treating this combination of factors. MATERIALS AND METHOD This study analyses the outcomes of five patients with the following inclus...