نتایج جستجو برای: bone marrow mesenchymal stem cells
تعداد نتایج: 1748257 فیلتر نتایج به سال:
The aim of this study was to the effect of aquatic activity and alogenic bone marrow derived mesenchymal stem cells fortified with Platelet-Rich Plasma in treatment of Achilles tendon in rat. 74 Sprague-Dawley rats were selected and tendon injury was formed in 69 of them. Subsequently, these rats were randomly divided into 8 groups and 5 rats which were without any injuries were chosen as the ...
low-intensity laser therapy (lilt) is defined to supply direct biostimulative light energy to the cells. while several studies have demonstrated that lilt has stimulating effects on bone cells and can accelerate the repair process of the bone, others reported delayed fracture healing or no effects after lilt. the aim of this article was to review the studies evaluating the biomodulation effects...
The stem cells that maintain and repair the postnatal skeleton remain undefined. One model suggests that perisinusoidal mesenchymal stem cells (MSCs) give rise to osteoblasts, chondrocytes, marrow stromal cells, and adipocytes, although the existence of these cells has not been proven through fate-mapping experiments. We demonstrate here that expression of the bone morphogenetic protein (BMP) a...
STUDY DESIGN Posterolateral lumbar transverse process fusion was carried out using cultured mesenchymal stem cells with or without bone morphogenetic protein (BMP) and basic fibroblast growth factor (FGF). OBJECTIVES To determine the ability of BMP and basic FGF to enhance the efficacy of bone marrow-derived mesenchymal stem cells in lumbar arthrodesis. SUMMARY OF BACKGROUND DATA Our previo...
Purpose: The aim of this study is to evaluate the effects of prepared serum from rat peripheral blood on growth and viability of rat bone marrow-derived mesenchymal stem cells (MSCs) in vitro. Materials and Methods: Bone marrow cells prepared from rat’s tibia and femur central canal were cultured either in medium containing fetal bovin serum (FBS) or rat peripheral blood-derived serum (PBDS) f...
stem cells are self-renewing cells that can be differentiated into other cell types. conventional in vitro models for studying stem cells differentiation are usually preformed in two-dimensional (2d) cultures. the design of three-dimensional (3d) in vitro models which ideally are supposed to mimic the in vivo stem cells microenvironment is potentially useful for inducing stem cell derived tissu...
background: mesenchymal stem cells (mscs) can be expanded and differentiated into many mature cell types including smooth muscle cells (smcs). in addition to growth factor, cyclic stretch contributes to differentiation of stem cells. mechanical stimuli are critical to morphological changes, development, regeneration, differentiation and pathology of mesenchymal tissues. the aim of this study is...
We hypothesized that RNA interference to silence Nogo-66 receptor gene expression in bone marrow mesenchymal stem cells before transplantation might further improve neurological function in rats with spinal cord transection injury. After 2 weeks, the number of neurons and BrdU-positive cells in the Nogo-66 receptor gene silencing group was higher than in the bone marrow mesenchymal stem cell gr...
in the bone marrow, there are certain populations of stem cell sources with the capacity to differentiate into several different types of cells. ideally, cell transplants would be readily obtainable, easy to expand and bank, and capable of surviving for sufficient periods of time. bone marrow mesenchymal stem cells (bm-mscs) possess all of these characteristics. one of the most important benefi...
Background: MSCs have been isolated from a variety of mammals by the plastic adherence method. However, this method can be problematic due to the unwanted growth of hematopoietic cells and non-MSCs. The potential of MSCs to differentiate along multiple lineages is the key to the identification of stem cell populations in the absence of molecular markers. In the present study, we describe a homo...
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