BACKGROUND Bone marrow-derived stem cell transplantation is a potentially viable therapeutic option for the treatment of neurodegenerative disease. MATERIAL/METHODS We have isolated bone marrow stem cells by standard method. We then evaluated the survival of rats' bone marrow mononuclear cells implanted in rats' brain. The cells were extracted from rats' femurs, and marked for monitoring purp...

The proliferative capacity of bone marrow cells from thymus-deprived nude mice was investigated in lethally irradiated recipients. Although the colony-forming capacity of these cells was found to be similar to that of normal littermates, a reduction in the number of nucleated cells was observed in the bone marrow of nude mice. Moreover when the radioprotective effect of such cells was studied, ...

  Background and Objectives: Bone marrow necrosis (BMN) is a rare and ominous complication of wide variety of diseases including hematologic malignancy. This study was performed to identify frequency and the underlying associated diseases of marrow necrosis. Materials and Methods: In this descriptive study, totally 850 bone marrow trephine biopsies related to living patients at the Pathology ...

OBJECTIVES Intracerebral injection of bone marrow stromal cells (BMSCs) is being investigated as a therapeutic tool to prevent Alzheimer's disease (AD). Our aim was to investigate the effects of BMSCs by intrathecal injection in AD rat model. MATERIALS AND METHODS BMSCs were obtained from the bone marrow of Wistar rat and transplanted into AD rat model via intrathecal injection. The rat model...

上島 久 正,鹿 島正俊,榎 本宏子,松 岡 理:放 射線 医学 総合研 究所 千葉市穴川4丁 目9番1号 〒260 Polymeric Plutonium/Hematopoietic Activity/Bone Marrow The hematopoietic activity in the bone marrow was investigated in male CF#1 mice at 28 and 56 days after intravenous injection of polymeric plutonium-239 at the dose level of 15 ƒÊCi/kg, 10 ƒÊCi/kg and 5 ƒÊCi/kg of body weight. The number of nucleated cells in the femoral marrow dec...

BACKGROUND There are a growing number of patients with end-stage coronary artery disease (CAD) and refractory angina. Angiogenesis may be induced by intramyocardial injection of autologous bone marrow stem cells, intensified by inflammation around channels performed by laser. AIM To assess the effect of a combined treatment consisting of transmyocardial laser revascularisation (TLMR) and intr...

Radiation accidents.-Flynn outlined in detail all the available information on the Los Alamos radiation accident of December 1958. The accident occurred in a plutonium salvage operation. Supportive therapy probably prevented the exposed person from dying almost immediately from a shock-like syndrome. He died 36 hours after the accident, from central nervous system damage. Vos reviewed newspaper...

hematopoietic stem/progenitor cells (hspcs) which give rise to different blood cell types are present within the bone marrow microenvironment, especially in flat bones such as skull, vertebrae, pelvis and chest. interacting factors such as stromal derived factor-1/cxcr4, very late antigen-4/vascular cell adhesion molecule-1, lymphocyte function-associated antigen-1/ intercellular adhesion molec...