background : children suffering from cancer always require pain relief and reduce anxiety when undergoing painful procedures. the aim of this study is to compare the effect of pethedine and ketamine administration in cancer-diagnosed children undergoing bone marrow aspiration and biopsy procedures. subjects and methods : a randomized, double-blinded, crossover trial was carried out on 57 childr...

Bone marrow aspiration can determine the metastatic deposits, degree of cellularity and fibrosis readily. A retrospective analysis of bone marrow aspiration and biopsy, in children and adult patients with hematological anomalies, were performed in 674 cases for different indication of hematological abnormalities from January 2013 to March 2014. Cases were analyzed in detail regarding clinical, ...

introduction: we aimed at evaluating the clinical, laboratory and echocardiography effects of intracoronary administration of autologous bone marrow stem cell transplantation in different clinical entities of chronic heart failure (hf) patients.   methods: this procedure was carried out during an interventional study conducted in the cardiology department from jan 2012 to apr 2013. the hf patie...

subtropics and is endemic in India1. In India, Wuchereria bancrofti accounts for 90% of the total filarial infections2. The disease can present as silent clinical disease or as lymphadenitis, lymphangitis or elephantiasis1. The diagnosis is conventionally based on demonstration of microfilaria in the peripheral blood smear. There are very few case reports describing microfilariae in bone marrow...

Acute myelofibrosis is characterized by pancytopenia of sudden onset, megakaryocytic hyperplasia, extensive bone marrow fibrosis, and the absence of organomegaly. Acute myelofibrosis in patients with acute lymphoblastic leukemia is extremely rare. We report a 4-year-old boy who was diagnosed as having acute massive myelofibrosis and acute lymphoblastic leukemia. Performing bone marrow aspiratio...

It is now universally agreed that examination of bone marrow aspiration material is essential for unravelling many haematological problems. In some cases, however, it is extremely difficult, or even impossible, to obtain specimens, as for example in the myelosclerotic and refractory anaemias. In the former, examination of the bone itself would be of value, and in the latter one would like to se...

Bone marrow fibrosis leading to dry tap aspiration and often associated with blast crisis has previously been reported in both Chronic myeloid leukemia Primary myelofibrosis. The similarities between these two conditions terms of clinical presentation morphology can really create a diagnostic dilemma. Here we present case 32 year old lady which closely resembled myelofibrosis transformation. Al...

In an attempt to see if buffy coat smear examination might be an alternative to bone marrow aspiration for predicting relapse, 98 consecutive bone marrow aspirates from 96 children with acute lymphoblastic leukaemia were examined blind with buffy coat and peripheral blood from the same patients. The 28 bone marrow aspirates from children no longer on treatment were all normal, and routine aspir...

We report a case of exclusive involvement of lymph node in leishmaniasis presenting as generalized lymphadenopathy. The diagnosis of lymphatic leishmaniasis was confirmed by the presence of Leishmania donovani body in fine needle aspiration cytology, positive direct agglutination test and anti-rK39 antibodies. The bone marrow aspiration was negative for Leishmania donovani body. This is the fir...