Recently it has been demonstrated that there are differences between sheep and goats in respect to adaptation to a calcium-restricted diet. It was the aim of the present study to evaluate whether species-specific peculiarities also occur when calcium homoeostasis is challenged by lactation. Therefore, we investigated the time courses of plasma parameters related to calcium homoeostasis (calcium...

The phase 2 LEO study showed that everolimus (EVE) plus letrozole (LET) with ovarian suppression increased progression-free survival (PFS) in tamoxifen-exposed premenopausal women hormone receptor-positive, HER2-negative metastatic breast cancer visceral metastases. Here we report final outcomes from the study, and results of exploratory analyses bone turnover marker changes bone-specific progr...

Background: Bone Mineral density (BMD) is considered as one of the golden tool to measure bone quality in which two measurements namely T- Score and Z –score are used report BMD test results. Whenever there deterioration it associated with low skeletal mass. Creatinine a chemical waste molecule that generated from this muscle metabolism. good marker for However, limited studies have been done t...

BACKGROUND The current study aimed to compare the measurements of the mandible morphology using 3D cone beam computed tomography (CBCT) images with those using 2D CBCT-synthesized cephalograms; to quantify errors in measurements based on 2D synthesized cephalograms; and to clarify the effects such errors have on the description of the mandibular growth. METHODS Mandibles of six miniature pigs...

Abstract An automatic markerless knee tracking and registration algorithm has been proposed in the literature to avoid marker insertion required by conventional computer-assisted surgery, resulting a shorter less invasive surgical workflow. However, such an considers intact femur geometry only. The bone surface modification is inevitable due intra-operative intervention. mismatched corresponden...

OBJECTIVES Static radiostereometric analysis (RSA) using implanted markers is considered the most accurate system for the evaluation of prosthesis migration. By using CT bone models instead of markers, combined with a dynamic RSA system, a non-invasive measurement of joint movement is enabled. This method is more accurate than current 3D skin marker-based tracking systems. The purpose of this s...

Akin osteotomy is a common component of hallux valgus surgery. Holding the osteotomy in good position with a well placed staple can prove difficult. To aid this, a marker pen is used to apply ink to the tip of the proximal limb of the staple (Fig 1). A hole is drilled in the distal bone and the non-inked staple limb is inserted while the osteotomy is held in the desired position. This causes tr...

objective(s): although many researchers have confirmed induction of germ cells from bone marrow mesenchymal stem cells (bmmscs), there are no reports that confirm spontaneous differentiation of germ cells from bmmscs. in this study, we have evaluated the effect of adult sertoli cell condition medium (sccm) as a mutative factor in the induction of germ cells from bmmscs. materials and methods: b...

Interleukin-1 (IL-1), a cytokine produced by bone marrow cells and bone cells, has been implicated in the pathogenesis of postmenopausal osteoporosis because of its potent stimulatory effects on bone resorption in vitro and in vivo. To investigate whether IL-1 plays a direct causal role in post ovariectomy bone loss, 6-mo-old ovariectomized rats were treated with subcutaneous infusions of IL-1 ...

Akin osteotomy is a common component of hallux valgus surgery. Holding the osteotomy in good position with a well placed staple can prove difficult. To aid this, a marker pen is used to apply ink to the tip of the proximal limb of the staple (Fig 1). A hole is drilled in the distal bone and the non-inked staple limb is inserted while the osteotomy is held in the desired position. This causes tr...