The culture system of bone marrow mesenchymal stem cells (bmMSCs) in the normoxic environment does not imitate hypoxic milieu typical biological conditions, thus conditions may improve survival, and growth attributes bmMSCs during vitro culture. Therefore, present study was conducted at ICAR-CIRG, Makhdoom year 2020 with objective to investigate changes characteristics cultured caprine (cbmMSCs...

Purpose: Exosomes are natural nanoparticles that participate in intercellular communication through molecular transport. Recently, due to their membrane vesicular structure and surface proteins, exosomes have been used extensively the research field of drug delivery. Osteoporosis is an inflammation which cellular balance bone tissue disturbed reduces density making prone abnormal fractures with...

C-kit+ cardiac stem cells (CSCs) were isolated from neonatal rat and tested for the expression of Nkx2.5 and GATA-4 genes which are important in cardiac development. C-kit+ CSCs were plated into the well below the insert of transwell inserts and bone marrow mesenchymal stem cells (BMMSCs) were plated into the inserts. The expression of cardiac Troponin T (cTnT), p27, CDK2, transforming growth f...

Osteogenesis is a complex series of events involving the differentiation of mesenchymal stem cells to generate new bone. In this study, we examined the effect of pulsed electromagnetic fields (PEMFs) on cell proliferation, alkaline phosphatase (ALP) activity, mineralization of the extracellular matrix, and gene expression in bone marrow mesenchymal stem cells (BMMSCs) during osteogenic differen...

Multipotent mesenchymal stromal cells derived from human placenta (pMSCs), and unrestricted somatic stem cells (USSCs) derived from cord blood share many properties with human bone marrow-derived mesenchymal stromal cells (bmMSCs) and are currently in clinical trials for a wide range of clinical settings. Here we present gene expression profiles of human cord blood-derived unrestricted somatic ...

Comment on: Jiang et al. Gene expression profiling suggests a pathological role of human bone marrow-derived mesenchymal stem cells in aging-related skeletal diseases. Aging 2011; this issue. In this issue of Impact Aging, Jiang et al. report key differences in the patterns of expressed mRNAs in bone-marrow mesenchymal stem cells (bmMSCs) of young donors compared with old human donors.

conclusions according to our results, silymarin injection caused significant differentiation of mscs to neurons and neuroglia that could be a promising approach for treating a variety of brain injuries. results expression of cd29 and cd90 markers that are characteristic of bmmscs were confirmed by flow cytometry experiments. the data demonstrated that proliferation and number of progenitor cell...

Submit Manuscript | http://medcraveonline.com Abbreviations: CMGG: Carboxymethyl Guar Gum; BMMscs: Bone Marrow Derived Mesenchymal Stem Cells; DMEM: Dulbecco’s Modified Eagle Medium; FBS: Foetal Bovine Serum; Pen-Strep: Penicillin-Streptomycin; LPS: Lipopolysaccharide; Cocl2.6H2O: Cobalt Chloride Hexahydrate; PBS: Phosphate Buffered Saline; EDTA: Ethylene Diamine Tetra Acetic Acid; MTT: 3-(4, 5...

Human mesenchymal stem cells (hMSCs) display immunosuppressive properties in vitro and the potential has also been transferred successfully to clinical trials for treatment of autoimmune diseases. OX-2 (CD200), a member of the immunoglobulin superfamily, is widely expressed in several tissues and has recently been found from hMSCs. The CD200 receptor (CD200R) occurs only in myeloid-lineage cell...