A gaschromatographic method is presented for the determination of thiopental (and of its metabolite pentobarbital) in cases of severe head injuries treated by induction of therapeutic barbiturate coma. To 1 ml serum the internal standard and saturated ammonium sulphate solution are added. The mixture is extracted by chloroform and the concentrated organic phase is injected into the gaschromatog...

In addition, due to the nature of ABG testing, clinicians cannot afford to waste time or resources when making decisions based on an ABG sample analysis. To ensure accurate results for such decision-making, it is imperative that the analytical process be as standardized and finely calibrated as possible. For example, variations in technique in the areas of specimen preparation, turnaround time ...

Accurate measurement of blood glucose levels in the newborn is important as hypoglycaemia and hyperglycaemia are common treatable conditions and there is evidence linking both with detrimental clinical outcomes. Point of care (POC) glucose testing provides rapid results with small sample volumes and therefore clinical care can be modified quickly if needed. However the common thresholds for the...

SEVERINGHAUS, JOHN W. Blood gas calculator. J. Appl. Physiol. 21(3): I 108-1 I 16. 1966.-A slide rule is described whose scales yield direct solutions of the following blood gas problems: r) the whole blood oxygen dissociation curve of man with variable temperature, pH, and base excess; 2) the effect of anaerobic temperature change on blood Pea , Pcoz , and pH; 3) the true oxygen consumption fr...

With increasing use of arterial blood gas analysis in various ward and other hospital settings to aid medical diagnosis and management, nurses who can interpret results are often able to initiate earlier interventions and understand the reasons for medical interventions. This article enables nurses to interpret such results.

Several aspects of mass spectrometry and gas chromatography-mass spectrometry are reviewed, including ionization methods, repetitive scanning, selected ion monitoring, and stable isotope measurement. I discuss the application of these and other mass spectrometry methods to the investigation of compound classes relevant to clinical chemistry, to the assessment of inborn errors of metabolism, and...

Quinolinic acid was first identified in uremic serum by use of gas chromatography/mass spectrometry. Quantification by selected ion monitoring revealed that the serum concentration of quinolinic acid was markedly increased in chronic hemodialysis patients, and that the acid could be removed by conventional hemodialysis. The serum concentration of quinolinic acid was weakly but significantly cor...

We have designed and fabricated the first single-wafer proportional micro control valve with built-in capacitive displacement sensing. The displacement sensor can facilitate high-speed active proportional control of gas flow through the valve. This is an essential requirement for non-invasive blood pressure waveform monitoring based on following the arterial pressure with a counter pressure. We...