Intracranial haemorrhage in early childhood is associated with a wide variety of causes such as trauma, vascular malformations (aneurysm and arteriovenous malformation), haemorrhagic infarction, brain tumours or blood coagulation disorders (congenital or acquired from coagulation factors). Vitamin K deficiency causes blood coagulation disturbances that can lead to intracranial haemorrhage [1]. ...

Background As for other pathologies, the pathogenesis of venous thrombo-embolism (VTE) is multifactorial. A comprehensive understanding of the pathogenesis of venous thrombosis is essential for identifying patients at increased risk as in elderly patients with congestive heart failure (CHD) and with presence of chronic venous insufficiency (IVC). Eberhard Mammen postulated immobility as the lea...

Murine lymphoid cells respond rapidly to bacterial lipopolysaccharide or antigen-antibody complexes to initiate or accelerate the blood coagulation pathways. The monocyte or macrophage has been identified as the cellular source, although lymphocyte collaboration is required for the rapid induction of the procoagulant response. This procoagulant activity is identified in the present study as a d...