Prostatic carcinoma is the most commonly diagnosed tumor among men over 40 which results in over 30,000 deaths each year in the United States. Previous studies indicated that tumor cell lines produce and release several growth regulatory factors into their condition media and so far a number of human tumor cell-derived suppressor factors have been isolated that affect normal immune functions. I...

background: the canonical wnt signal transduction (or the wnt/β-catenin pathway) plays a crucial role in the development of animals and in carcinogenesis. beta-catenin is the central component of this signaling pathway. the activation of wnt/β-catenin signaling results in the cytoplasmic and nuclear accumulation of β-catenin. in the nucleus, β-catenin interacts with the tcf/lef transcription fa...

introduction: squamous cell carcinoma (scc) is the most common head and neck malignancy. smoking, alcohol consumption, viral infections, exposure, oral hygiene, and dietary, genetic, and occupational factors are the most important etiologic factors. the aim of this study was determining the incidence of etiologic factors in head and neck scc.  materials and methods: this is a cross-sectional su...

more than eighty percent of patients with coronary heart diseases (chd) have conventional risk factors. prevalence of well known risk factors seems to show a different pattern in younger patients and individual above 55 years. to evaluate the pattern of conventional chd risk factors in healthy individuals in two different age groups. a large scale population based survey of 31999 individuals fr...

This work described and compared the hematological findings of 25 clinically healthy Harris’s hawks(Parabuteo unicinctus) in captivity at two different tropical locations: 16 samples from Aguascalientes, which altitude is 1878 mean sea level, and nine samples from Amecameca which altitude is 2650 mean sea level. Blood samples were collected from the brachial vein of each raptor under p...

background hemolyis of red blood cells is a serious toxic effect commonly found among patients envenomed by hemiscorpius lepturus scorpion. objectives the aim of the present study was to evlaute the efficay of the avaible polyvalent antivneom in preventing this phenomena. materials and methods using a red blood cell fragility test, the anti-hemolytic effectiveness of a new antivenom serum again...

background: the development of anti-red blood cell alloantibodies remains a major problem in transfusion of blood in thalassemia major patients. also, autoantibodies can result in clinical hemolysis and difficulty in cross-matching blood. we studied the frequency of red blood cell alloimmunization and autoimmunization among thalassemia patients who received regular transfusions in ilam province...

objectives: the study of erythropoiesis needs to develop the methods for erythroid progenitor cells (epcs) culture using stem cell potency to differentiate into variety of hematopoietic cells lineages. in this study, we induced differentiation of cord blood stem cells into erythroid progenitor cells in a semisolid culture media. materials and methods: cord blood mononuclear cells were isolate...