Linear cutaneous lupus erythematosus (LCLE) is rare. The LCLE was proposed by Abe et al. [1] for discoid lupus erythematosus (DLE) with a linear configuration in 1988. It occurs mainly in children and young adults. Lesions appear as linear unilateral erythematous plaques following the Blaschko lines and are observed most frequently on the face, although the neck, trunk and extremities may also ...

Melanomas usually present as oval lesions in which the borders may be irregular. Other morphological features of melanoma include clinical asymmetry, variable color, diameter greater than 6 mm and evolving lesions. Two males whose melanoma in situ presented as linear skin lesions are described and cutaneous malignancies that may appear linear in morphology are summarized in this report. A medic...

We report six persons mosaic for a chromosome anomaly. All were mentally retarded and dysmorphic. Unilateral or asymmetrical features were found in all cases, in one an unusual transverse terminal limb anomaly, and in the others various degrees of hemiatrophy of the left side of the body. Five of the subjects had skin pigmentary anomalies which were distributed in the lines of Blaschko. The abn...

Incontinentia Pigmenti, also known as Bloch-Sulzberger syndrome, is a rare X-linked dominant disorder considered to be lethal in males. The syndrome usually presents at birth or shortly thereafter and the skin rash evolves in the classic four stages of vesicular, verrucous, hyperpigmented, and hypopigmented lesions following a blaschko linear distribution. Here we present an unusual case of Inc...

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Alles, G. A. (1939). Amer. J. Physiol. 126, 420P. Blaschko, H. (1958). In 5-Hydroxytryptamine, pp. 50-57. Ed. by Lewis, G. P. London: Pergamon Press Ltd. Blaschko, H. & Himms, J. M. (1954). J. exp. Biol. 31, 1. Davison, A. N., Lessin, A. W. & Parkes, M. W. (1957). Experientia, 18, 329. Hope, D. B. (1959). Symp. biochem. Soc. 17, 93. Kobayashi, Y. (1957). Arch. Biochem. Biophy8. 71, 352. Kobayas...

With Dr. Fischer's long interest in muscle physiology and with his background in Germany, I thought that my personal experiences in Professor Otto Meyerhof's laboratory in Heidelberg, 1931-1932, might be of interest. This laboratory was at that time one of the outstanding centers for research in muscle physiology and chemistry. The laboratory was called the Kaiser Wilhelm-Institute fiir Medizin...